Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BBP08_RS08345 Genome accession   NZ_CP016501
Coordinates   1651874..1652629 (-) Length   251 a.a.
NCBI ID   WP_000425368.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain WC1535     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1646874..1657629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBP08_RS08325 (BBP08_08035) - 1647244..1648476 (-) 1233 WP_000173347.1 cysteine desulfurase -
  BBP08_RS08330 (BBP08_08040) sufD 1648478..1649740 (-) 1263 WP_000031278.1 Fe-S cluster assembly protein SufD -
  BBP08_RS08335 (BBP08_08045) sufC 1649777..1650547 (-) 771 WP_000114502.1 Fe-S cluster assembly ATPase SufC -
  BBP08_RS08340 (BBP08_08050) - 1650712..1651872 (-) 1161 WP_000612109.1 glycosyltransferase family 4 protein -
  BBP08_RS08345 (BBP08_08055) mecA 1651874..1652629 (-) 756 WP_000425368.1 adaptor protein MecA Regulator
  BBP08_RS08350 (BBP08_08060) - 1652749..1653588 (-) 840 WP_000905325.1 undecaprenyl-diphosphate phosphatase -
  BBP08_RS08355 (BBP08_08065) - 1653634..1655508 (-) 1875 WP_000710500.1 DUF2207 domain-containing protein -
  BBP08_RS08360 (BBP08_08070) - 1655644..1657194 (+) 1551 WP_000722386.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29010.84 Da        Isoelectric Point: 4.2155

>NTDB_id=188646 BBP08_RS08345 WP_000425368.1 1651874..1652629(-) (mecA) [Streptococcus agalactiae strain WC1535]
MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSLLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQAEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=188646 BBP08_RS08345 WP_000425368.1 1651874..1652629(-) (mecA) [Streptococcus agalactiae strain WC1535]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATCGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTCATGGATGAATTAGACTTGCCAGAAAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACATT
GGAACAATCGCTGTTGGAAAAAGGGGATACGGATGCCCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAAGCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACCAAGCTACTTTGCTAATTTGATGTATGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.742

98.805

0.669
  mecA Streptococcus thermophilus LMD-9

59.438

99.203

0.59
  mecA Streptococcus thermophilus LMG 18311

58.635

99.203

0.582
  mecA Streptococcus pneumoniae Rx1

46.614

100

0.466
  mecA Streptococcus pneumoniae D39

46.614

100

0.466
  mecA Streptococcus pneumoniae R6

46.614

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.614

100

0.466

Multiple sequence alignment