Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   BAY21_RS03215 Genome accession   NZ_CP016439
Coordinates   612789..614306 (-) Length   505 a.a.
NCBI ID   WP_059257356.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 607789..619306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BAY21_RS03195 (BAY21_03195) der 608694..610004 (-) 1311 WP_011225483.1 ribosome biogenesis GTPase Der -
  BAY21_RS03200 (BAY21_03200) dnaI 610110..611012 (-) 903 WP_002946786.1 primosomal protein DnaI -
  BAY21_RS03205 (BAY21_03205) - 611016..612191 (-) 1176 WP_011225482.1 DnaD domain protein -
  BAY21_RS03210 (BAY21_03210) nrdR 612188..612667 (-) 480 WP_002949642.1 transcriptional regulator NrdR -
  BAY21_RS03215 (BAY21_03215) covS 612789..614306 (-) 1518 WP_059257356.1 HAMP domain-containing sensor histidine kinase Regulator
  BAY21_RS03220 (BAY21_03220) covR 614303..614992 (-) 690 WP_002949638.1 response regulator transcription factor Regulator
  BAY21_RS03225 (BAY21_03225) - 615148..615684 (-) 537 WP_041826965.1 DUF177 domain-containing protein -
  BAY21_RS03230 (BAY21_03230) rsmG 615981..616694 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BAY21_RS03235 (BAY21_03235) - 616764..618128 (+) 1365 WP_082302969.1 TrkH family potassium uptake protein -
  BAY21_RS03240 (BAY21_03240) - 618168..618839 (+) 672 WP_002946492.1 potassium channel family protein -
  BAY21_RS10920 - 618856..619026 (-) 171 Protein_634 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57522.90 Da        Isoelectric Point: 5.2689

>NTDB_id=188236 BAY21_RS03215 WP_059257356.1 612789..614306(-) (covS) [Streptococcus thermophilus strain CS8]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=188236 BAY21_RS03215 WP_059257356.1 612789..614306(-) (covS) [Streptococcus thermophilus strain CS8]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCATGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.821

99.406

0.943

Multiple sequence alignment