Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | FORC40_RS00240 | Genome accession | NZ_CP016398 |
| Coordinates | 50676..52304 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186608.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain FORC_040 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 23965..72377 | 50676..52304 | within | 0 |
| SCCmec | 42351..58846 | 50676..52304 | within | 0 |
Gene organization within MGE regions
Location: 23965..72377
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FORC40_RS00110 (FORC40_0019) | yycF | 24423..25124 (+) | 702 | WP_000101976.1 | response regulator YycF | - |
| FORC40_RS00115 (FORC40_0020) | walK | 25137..26963 (+) | 1827 | WP_000871607.1 | cell wall metabolism sensor histidine kinase WalK | - |
| FORC40_RS00120 (FORC40_0021) | yycH | 26956..28290 (+) | 1335 | WP_001060140.1 | two-component system activity regulator YycH | - |
| FORC40_RS00125 (FORC40_0022) | - | 28291..29079 (+) | 789 | WP_001104168.1 | two-component system regulatory protein YycI | - |
| FORC40_RS00130 (FORC40_0023) | - | 29468..30268 (+) | 801 | WP_000088649.1 | MBL fold metallo-hydrolase | - |
| FORC40_RS00135 (FORC40_0024) | adsA | 30496..32814 (+) | 2319 | WP_000645771.1 | LPXTG-anchored adenosine synthase AdsA | - |
| FORC40_RS00145 (FORC40_0026) | rlmH | 33182..33661 (+) | 480 | WP_000704775.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| FORC40_RS00150 (FORC40_0027) | - | 33983..35239 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| FORC40_RS00155 (FORC40_0028) | - | 35654..35893 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| FORC40_RS00160 (FORC40_0029) | - | 35925..36599 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| FORC40_RS00165 | - | 36690..37673 (-) | 984 | Protein_27 | protein rep | - |
| FORC40_RS00170 (FORC40_0032) | mobV | 37917..39179 (-) | 1263 | WP_029163598.1 | MobV family relaxase | - |
| FORC40_RS00175 (FORC40_0033) | bleO | 39686..40090 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| FORC40_RS00180 (FORC40_0034) | aadD1 | 40307..41068 (-) | 762 | WP_001014230.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| FORC40_RS00185 (FORC40_0035) | - | 41270..41944 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| FORC40_RS00190 (FORC40_0036) | - | 42000..42305 (+) | 306 | Protein_32 | MaoC/PaaZ C-terminal domain-containing protein | - |
| FORC40_RS00195 (FORC40_0037) | mecA | 42351..44360 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| FORC40_RS00200 (FORC40_0038) | - | 44457..45443 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| FORC40_RS00205 (FORC40_0039) | - | 45433..45675 (+) | 243 | Protein_35 | type I restriction enzyme endonuclease domain-containing protein | - |
| FORC40_RS00210 (FORC40_0040) | - | 45942..47141 (+) | 1200 | WP_073392450.1 | IS110-like element ISSep2 family transposase | - |
| FORC40_RS00215 (FORC40_0041) | - | 47238..48836 (-) | 1599 | Protein_37 | IS1182 family transposase | - |
| FORC40_RS00220 (FORC40_0042) | - | 48885..49391 (-) | 507 | WP_001092189.1 | DUF1643 domain-containing protein | - |
| FORC40_RS00225 (FORC40_0043) | - | 49406..49717 (-) | 312 | WP_000700851.1 | DUF960 family protein | - |
| FORC40_RS00235 (FORC40_0044) | - | 49804..50154 (-) | 351 | WP_000849672.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| FORC40_RS00240 (FORC40_0045) | ccrB | 50676..52304 (-) | 1629 | WP_001186608.1 | cassette chromosome recombinase CcrB | Machinery gene |
| FORC40_RS00245 (FORC40_0046) | ccrA | 52326..53675 (-) | 1350 | WP_002486033.1 | cassette chromosome recombinase CcrA | Machinery gene |
| FORC40_RS00250 (FORC40_0047) | cch1 | 53909..55702 (-) | 1794 | WP_000079474.1 | cassette chromosome replicative helicase | - |
| FORC40_RS00255 (FORC40_0048) | ssb | 55702..55998 (-) | 297 | WP_000273823.1 | cassette chromosome ssDNA-binding protein | - |
| FORC40_RS00260 (FORC40_0049) | - | 56191..57237 (-) | 1047 | WP_001042023.1 | hypothetical protein | - |
| FORC40_RS00265 (FORC40_0050) | - | 57692..58846 (+) | 1155 | WP_000912116.1 | ATP-binding protein | - |
| FORC40_RS00270 (FORC40_0051) | - | 58876..59676 (+) | 801 | WP_000749913.1 | abortive infection family protein | - |
| FORC40_RS00275 (FORC40_0052) | - | 59859..60794 (+) | 936 | WP_000251226.1 | dsDNA nuclease domain-containing protein | - |
| FORC40_RS00280 (FORC40_0053) | - | 60787..61395 (+) | 609 | WP_029163516.1 | hypothetical protein | - |
| FORC40_RS14390 (FORC40_0054) | - | 61392..62459 (+) | 1068 | WP_223286853.1 | hypothetical protein | - |
| FORC40_RS00290 (FORC40_0055) | - | 62706..63692 (-) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| FORC40_RS00295 (FORC40_0056) | - | 64001..64204 (+) | 204 | WP_000398680.1 | DUF6007 family protein | - |
| FORC40_RS00300 (FORC40_0057) | - | 64253..64549 (+) | 297 | WP_000179888.1 | TfoX/Sxy family protein | - |
| FORC40_RS00305 (FORC40_0058) | - | 64758..65360 (+) | 603 | WP_000908959.1 | hypothetical protein | - |
| FORC40_RS00310 (FORC40_0059) | - | 65652..66566 (-) | 915 | WP_000814441.1 | alpha/beta hydrolase | - |
| FORC40_RS00315 (FORC40_0060) | - | 66745..67299 (+) | 555 | WP_020977952.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
| FORC40_RS14550 | - | 67388..67501 (+) | 114 | Protein_57 | hypothetical protein | - |
| FORC40_RS00320 (FORC40_0061) | - | 67529..68266 (+) | 738 | WP_001792407.1 | methyltransferase domain-containing protein | - |
| FORC40_RS00325 (FORC40_0062) | - | 68422..68904 (+) | 483 | WP_000410569.1 | hypothetical protein | - |
| FORC40_RS00330 (FORC40_0063) | - | 69110..70096 (+) | 987 | WP_000710561.1 | phosphatidylinositol-specific phospholipase C | - |
| FORC40_RS00335 (FORC40_0064) | - | 70317..71087 (+) | 771 | WP_000977794.1 | tandem-type lipoprotein | - |
| FORC40_RS00340 (FORC40_0065) | - | 71154..71921 (+) | 768 | WP_000649985.1 | tandem-type lipoprotein | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62654.83 Da Isoelectric Point: 9.7970
>NTDB_id=187985 FORC40_RS00240 WP_001186608.1 50676..52304(-) (ccrB) [Staphylococcus aureus strain FORC_040]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=187985 FORC40_RS00240 WP_001186608.1 50676..52304(-) (ccrB) [Staphylococcus aureus strain FORC_040]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
98.893 |
100 |
0.989 |