Detailed information NTG0185658

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A9I65_RS04250
• Genome accession: NZ_CP016073
• Coordinates: 967271..968314 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain 081661 isolate 20081661
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 962271..973314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9I65_RS04225 (A9I65_04225)	-	962525..963247 (+)	723	WP_014613476.1	glutamine amidotransferase	-
A9I65_RS04230 (A9I65_04230)	-	964217..965215 (-)	999	WP_037542644.1	aromatic acid exporter family protein	-
A9I65_RS04235 (A9I65_04235)	map	965312..966073 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
A9I65_RS04240 (A9I65_04240)	-	966171..966560 (+)	390	WP_014613479.1	hypothetical protein	-
A9I65_RS04245 (A9I65_04245)	liaF	966573..967274 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
A9I65_RS04250 (A9I65_04250)	vraS	967271..968314 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
A9I65_RS04255 (A9I65_04255)	vraR	968304..968933 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
A9I65_RS04260 (A9I65_04260)	-	969500..970081 (-)	582	WP_015729388.1	carbonic anhydrase	-
A9I65_RS04265 (A9I65_04265)	-	970114..971451 (-)	1338	WP_037542645.1	YihY/virulence factor BrkB family protein	-
A9I65_RS04270 (A9I65_04270)	-	971667..971954 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
A9I65_RS04275 (A9I65_04275)	-	971962..972420 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
A9I65_RS04280 (A9I65_04280)	-	972554..972757 (+)	204	WP_037542646.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=185658 A9I65_RS04250 WP_014613481.1 967271..968314(+) (vraS) [Staphylococcus pseudintermedius strain 081661 isolate 20081661]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=185658 A9I65_RS04250 WP_014613481.1 967271..968314(+) (vraS) [Staphylococcus pseudintermedius strain 081661 isolate 20081661]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839