Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   A9I65_RS00245 Genome accession   NZ_CP016073
Coordinates   52007..53353 (-) Length   448 a.a.
NCBI ID   WP_000816499.1    Uniprot ID   Q9R3W9
Organism   Staphylococcus pseudintermedius strain 081661 isolate 20081661     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 38550..53353 52007..53353 within 0


Gene organization within MGE regions


Location: 38550..53353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9I65_RS00175 (A9I65_00175) mecA 38550..40559 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  A9I65_RS00180 (A9I65_00180) mecR1 40656..42413 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  A9I65_RS00185 (A9I65_00185) mecI 42413..42784 (+) 372 WP_025904161.1 mecA-type methicillin resistance repressor MecI -
  A9I65_RS13420 psm-mec 42869..42937 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  A9I65_RS00190 (A9I65_00190) - 43257..44405 (+) 1149 WP_075773656.1 ROK family transcriptional regulator -
  A9I65_RS00200 (A9I65_00200) cstB 44519..45852 (-) 1334 Protein_38 persulfide dioxygenase-sulfurtransferase CstB -
  A9I65_RS00205 (A9I65_00205) - 45885..46948 (-) 1064 Protein_39 DsrE/DsrF/DrsH-like family protein -
  A9I65_RS00210 (A9I65_00210) cstR 47084..47344 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  A9I65_RS13080 - 47344..47982 (+) 639 Protein_41 sulfite exporter TauE/SafE family protein -
  A9I65_RS13840 (A9I65_00215) - 48036..48401 (-) 366 Protein_42 JAB domain-containing protein -
  A9I65_RS00220 (A9I65_00220) - 48394..48600 (-) 207 WP_001077283.1 hypothetical protein -
  A9I65_RS00225 (A9I65_00225) - 48602..49123 (-) 522 WP_000836008.1 DUF1643 domain-containing protein -
  A9I65_RS00230 (A9I65_00230) - 49142..49453 (-) 312 WP_000833212.1 DUF960 family protein -
  A9I65_RS00235 (A9I65_00235) - 49538..49888 (-) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  A9I65_RS00240 (A9I65_00240) - 50359..51986 (-) 1628 Protein_47 recombinase family protein -
  A9I65_RS00245 (A9I65_00245) ccrA 52007..53353 (-) 1347 WP_000816499.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 52138.19 Da        Isoelectric Point: 10.1760

>NTDB_id=185654 A9I65_RS00245 WP_000816499.1 52007..53353(-) (ccrA) [Staphylococcus pseudintermedius strain 081661 isolate 20081661]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=185654 A9I65_RS00245 WP_000816499.1 52007..53353(-) (ccrA) [Staphylococcus pseudintermedius strain 081661 isolate 20081661]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(168-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9R3W9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

78.174

100

0.783
  ccrA Staphylococcus aureus N315

72.383

100

0.725

Multiple sequence alignment