Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   A6J54_RS12000 Genome accession   NZ_CP020402
Coordinates   2020560..2022779 (-) Length   739 a.a.
NCBI ID   WP_172595951.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_215     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 2015560..2027779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J54_RS11970 (A6J54_11580) lptE 2015607..2016086 (-) 480 WP_002214127.1 LPS assembly lipoprotein LptE -
  A6J54_RS11975 (A6J54_11585) pgeF 2016138..2016917 (-) 780 WP_002233699.1 peptidoglycan editing factor PgeF -
  A6J54_RS15515 - 2017084..2017257 (+) 174 Protein_1950 IS5/IS1182 family transposase -
  A6J54_RS11985 (A6J54_11595) - 2017476..2018423 (+) 948 WP_002229204.1 bile acid:sodium symporter family protein -
  A6J54_RS11990 (A6J54_11600) rluD 2018576..2019700 (-) 1125 WP_080542307.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  A6J54_RS11995 (A6J54_11605) comL 2019699..2020502 (+) 804 WP_002217677.1 outer membrane protein assembly factor BamD Machinery gene
  A6J54_RS12000 (A6J54_11610) comA 2020560..2022779 (-) 2220 WP_172595951.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A6J54_RS15520 - 2022861..2023052 (+) 192 Protein_1955 hypothetical protein -
  A6J54_RS12005 (A6J54_11620) - 2023274..2024326 (+) 1053 WP_080542308.1 IS5 family transposase -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79808.47 Da        Isoelectric Point: 10.0892

>NTDB_id=185639 A6J54_RS12000 WP_172595951.1 2020560..2022779(-) (comA) [Neisseria meningitidis strain FDAARGOS_215]
MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWWAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
GTVGADRVLLHGGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPSAVLGVGTWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLISPLVNAVAIPWFSW
VLTPLALLGSVVPFASLQQLGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVFYRSPGVPENEVAVTVWDAGQGLSVSVQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRGYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=185639 A6J54_RS12000 WP_172595951.1 2020560..2022779(-) (comA) [Neisseria meningitidis strain FDAARGOS_215]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGTGCGGCGGCTTCGTTCGCGCTGCCGGTCGTGCCGCATTGGCT
GTTTTGGCTGGCGGCTTTTGCGGTTTTTGCTGTGTTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGGACGGAGGCGGCATTGTCTTCCCAATGGTGGGCAGAAGCCGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGTGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGTGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGTG
TGCACCCTGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGAATAGGCGGCGCG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
TAATTGGCAGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTAATGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCTGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCAGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGCG
TTTTGATGTTGGCGGCGTTTGCGTGGGCTTGGCGCAGGGGAAGATTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCGTCGGCGGTCTTGGGTGTGGGGACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGCTCGGGGCGTTTGCACGAGGGAAAACGGCAAACTGCTTTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCGCTGG
TTTTGCTCGGTTATCTGTTTGCTTCGCTGCCTTTAATCAGCCCTTTGGTCAATGCGGTGGCGATTCCGTGGTTTTCTTGG
GTATTGACGCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGTCTTTGCAACAGTTGGGGGCATTTTTGGCGGAATA
TACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCCGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGTTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTGTTTTACCGTTCACCCGGCGTGCCGGAAAATGAGGTTGCGGTTACGGTTTGGGATGCGGGGCAGGGTTTGTCGGT
GTCGGTTCAGACGGCAAATCATCATCTTTTGTTTGACACCGGAACGGCAGCGGCGGCGCAGATGGGGATTGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGTTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCTGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTTGAGTTTTTGATGCCGTCTGAACGCAAAAACATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTCTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAACATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAATTGCTGCGTACCGATTTGTCGGGCGCACTGCAATTCGGCTTGGGACGCGGCGGC
GTGAAGGCTCAACGTTTGAGAGGGTATAAATTCTATTGGCAGAAAAAACCGTTTGAATGA

Domains

Predicted by InterProScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-677)

Domain of unknown function (DUF4131) (DUF4131)

(8-167)

Competence protein (Competence)

(208-465)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

95.535

100

0.955

Multiple sequence alignment