Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   FBA2_RS04280 Genome accession   NZ_CP016028
Coordinates   844716..845387 (+) Length   223 a.a.
NCBI ID   WP_004270751.1    Uniprot ID   A0A1B2A7J9
Organism   Latilactobacillus curvatus strain FBA2     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 839716..850387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FBA2_RS04250 (FBA2_04250) - 839927..841114 (+) 1188 WP_004270744.1 FtsW/RodA/SpoVE family cell cycle protein -
  FBA2_RS04255 (FBA2_04255) - 841127..842215 (+) 1089 WP_064777098.1 CAP-associated domain-containing protein -
  FBA2_RS04260 (FBA2_04260) - 842235..842525 (+) 291 WP_064777099.1 YlbG family protein -
  FBA2_RS04265 (FBA2_04265) rsmD 842531..843085 (+) 555 WP_039099193.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  FBA2_RS04270 (FBA2_04270) coaD 843097..843591 (+) 495 WP_039099191.1 pantetheine-phosphate adenylyltransferase -
  FBA2_RS04275 (FBA2_04275) - 843593..844639 (+) 1047 WP_080563410.1 SepM family pheromone-processing serine protease -
  FBA2_RS04280 (FBA2_04280) comEA 844716..845387 (+) 672 WP_004270751.1 helix-hairpin-helix domain-containing protein Machinery gene
  FBA2_RS04285 (FBA2_04285) - 845446..845934 (+) 489 WP_107504407.1 ComE operon protein 2 -
  FBA2_RS04290 (FBA2_04290) comEC 846075..848189 (+) 2115 WP_235601712.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FBA2_RS04295 (FBA2_04295) holA 848190..849218 (+) 1029 WP_064777102.1 DNA polymerase III subunit delta -
  FBA2_RS04300 (FBA2_04300) rpsT 849273..849527 (-) 255 WP_004271117.1 30S ribosomal protein S20 -
  FBA2_RS04305 (FBA2_04305) rpsO 849804..850073 (+) 270 WP_004271112.1 30S ribosomal protein S15 -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24849.51 Da        Isoelectric Point: 9.9048

>NTDB_id=185453 FBA2_RS04280 WP_004270751.1 844716..845387(+) (comEA) [Latilactobacillus curvatus strain FBA2]
MWRDYWQRYRRFWWVPCLVIILLGGGVFWQHSRQQRFLSTNQQLMAQSTKRKVKAKPVKQKKSVSKGGFVDIKGAVAHPG
IYPICVAKTRLFEVLKQAGDVTEAADTSQLNLAQTLSDQLIIYVPTKGEAVQAEELVKAADEPQAATDNQAGASPISTDA
KINLNQADATQLQTLNGIGPKKAEQIIAYRDEQGQFKQIEDLQKVGGIGPKTFEQLRPQICVN

Nucleotide


Download         Length: 672 bp        

>NTDB_id=185453 FBA2_RS04280 WP_004270751.1 844716..845387(+) (comEA) [Latilactobacillus curvatus strain FBA2]
ATGTGGCGCGACTATTGGCAACGGTATCGTCGATTCTGGTGGGTACCTTGTTTGGTGATAATTTTACTTGGTGGTGGTGT
GTTTTGGCAGCATAGTCGGCAACAACGTTTTCTATCAACCAATCAACAATTGATGGCGCAATCAACTAAGCGAAAAGTGA
AGGCAAAACCCGTCAAACAGAAGAAAAGCGTCTCAAAAGGTGGGTTTGTCGATATTAAAGGCGCTGTGGCACATCCAGGG
ATTTATCCGATTTGTGTTGCAAAGACGCGTTTATTTGAGGTGCTGAAACAAGCGGGGGATGTGACCGAAGCAGCGGATAC
GAGTCAGTTGAACTTAGCGCAAACATTGAGTGACCAACTTATTATCTATGTGCCAACTAAGGGAGAAGCGGTGCAAGCCG
AAGAATTAGTGAAAGCGGCAGACGAGCCACAGGCTGCGACTGACAATCAAGCGGGAGCCAGTCCGATATCAACTGATGCT
AAAATCAACCTAAACCAAGCGGATGCGACACAATTGCAAACGCTAAATGGCATCGGTCCTAAAAAAGCTGAACAAATAAT
TGCATATCGGGATGAGCAAGGGCAGTTTAAACAAATCGAAGATCTTCAAAAAGTTGGGGGAATTGGGCCGAAAACGTTTG
AACAATTACGGCCACAAATTTGTGTTAATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(70-115)

Helix-hairpin-helix motif (HHH_3)

(160-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B2A7J9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Latilactobacillus sakei subsp. sakei 23K

64.53

100

0.677
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.368

Multiple sequence alignment