Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A9Y60_RS00280 Genome accession   NZ_CP016016
Coordinates   52318..55473 (-) Length   1051 a.a.
NCBI ID   WP_050156293.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 34530     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47318..60473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9Y60_RS00250 (A9Y60_00250) - 47677..48240 (-) 564 WP_002214615.1 ComF family protein -
  A9Y60_RS15490 - 48800..49173 (+) 374 Protein_48 hypothetical protein -
  A9Y60_RS00260 (A9Y60_00260) - 49359..49738 (-) 380 Protein_49 VOC family protein -
  A9Y60_RS00265 (A9Y60_00265) carA 49792..50925 (-) 1134 WP_003694721.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A9Y60_RS00280 (A9Y60_00280) pilC 52318..55473 (-) 3156 WP_050156293.1 PilC family type IV pilus tip adhesin Machinery gene
  A9Y60_RS00300 (A9Y60_00300) apbC 56882..57961 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  A9Y60_RS00310 (A9Y60_00310) - 58335..58844 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  A9Y60_RS00320 (A9Y60_00320) nadR 59185..59625 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  A9Y60_RS00325 (A9Y60_00325) hpaC 59740..60240 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1051 a.a.        Molecular weight: 115184.42 Da        Isoelectric Point: 9.9739

>NTDB_id=185159 A9Y60_RS00280 WP_050156293.1 52318..55473(-) (pilC) [Neisseria gonorrhoeae strain 34530]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGQAQAQTYKYAIVMNERKQPEVKWKGQYNQSALKDKGRERTFSHTSQKNKF
GITSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYGYDGIRCGSAQDCPK
LTYKTRFSFDNPNLVKTRGGLDRHTEPSRENSPIYKLKDHPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLV
YTTEGHRISLGNWQRETTAMAYYLNAKLHLLDKKQIENIAPGKTVRLGVLKPSIDVKTQNTGLSGLLNFWSKWDIKDNGQ
IPVKLGLPQVKAGRCINKPNPNKNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPG
RHSLAALDTQNIKSREPNFNSRQTVIRLPGGVYKINPVKNGGRVAGFNGNDGKNDTFGIYKDRLVTPEADEWSEVLLPWT
ARYYGNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHIFKKTGTDE
RSYELKLSYIPGTMERKDIENQDSTLAKELRTFAEKGYVGDRYGVDGGFVLRSITDDQDRQKHFFMFGAMGLGGRGAYAL
DLSKIDSNPVGVSMFDVQNESKNNGVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENKTALYVYDLGNGSGSLI
KKIEVQGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSSDKPSEWTVRTIFQGTKPITSAPAVSRLADKRVVIF
GTGSDLSEEDVVGKDQQYIYGIFDDDKGTGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSNGKGWVVRLREGE
RVTVKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHDSVAQYSGHKKTADGKSVPIGCMWK
NGKTACPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCG
IKRLSWREVFF

Nucleotide


Download         Length: 3156 bp        

>NTDB_id=185159 A9Y60_RS00280 WP_050156293.1 52318..55473(-) (pilC) [Neisseria gonorrhoeae strain 34530]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAGGCGCAAACGTATAAATACGCTATTGTGATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGA
AGGGTCAATATAATCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAAATTC
GGCATCACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCAC
AGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATT
GGATTCATACCACCCGGCCCGGGCTGGCAGGCTACGGCTACGACGGTATCCGTTGCGGAAGTGCCCAAGACTGTCCCAAA
CTTACCTATAAAACCCGATTTTCCTTCGATAATCCCAACTTGGTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCC
AAGCCGCGAAAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGGCGAGGGTA
CCGCCAAAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTC
TATACGACAGAAGGCCACCGTATTTCCCTTGGCAACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAA
GCTGCACCTGCTGGACAAAAAACAGATTGAAAATATCGCGCCAGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCA
TCGATGTGAAGACACAAAATACGGGGCTTAGCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAG
ATTCCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCAGGCCGCTGCATCAATAAACCGAACCCCAATAAGAATACCAAAGC
CCCTTCGCCGGCCCTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGG
TTTCTACCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGC
CGGCATTCCCTCGCCGCTTTGGATACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCG
ATTGCCGGGCGGCGTGTACAAGATCAACCCGGTCAAGAACGGCGGCCGGGTCGCGGGTTTTAATGGCAATGACGGCAAAA
ACGACACTTTCGGCATCTACAAGGACAGGCTCGTCACACCTGAGGCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACG
GCTCGGTATTACGGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATA
CAGCCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGA
TAACGGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACGGATGAA
CGCAGCTACGAACTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGC
CAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCAGCA
TTACAGATGACCAAGACAGGCAAAAACATTTCTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCGCATACGCCTTG
GATTTAAGCAAAATCGACAGCAACCCGGTCGGCGTTTCCATGTTTGATGTCCAAAACGAGAGTAAAAATAATGGCGTGAA
ATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATG
CGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGTATGATTTGGGAAACGGCAGTGGTAGTCTGATT
AAAAAAATCGAAGTGCAGGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGA
TATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCAGCGACAAGCCGTCCGAGTGGACTGTAC
GCACTATTTTCCAAGGCACAAAACCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTTATCTTC
GGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTAAGGATCAACAATATATTTACGGTATCTTTGACGACGATAA
GGGGACGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTACGAAGGAAAATA
ACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACGGTAAAGGGTGGGTAGTGAGATTGAGGGAAGGAGAA
CGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGTAGCTATACGGGTAATGACAAATGCGG
CGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGG
ATCACGATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCGACGGCAAGTCCGTCCCTATAGGCTGTATGTGGAAA
AACGGCAAAACCGCCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGA
CGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACC
GGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGT
ATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(526-862)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70

100

0.706

Multiple sequence alignment