Detailed information NTG0184654

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: A9E94_RS12665
• Genome accession: NZ_CP015954
• Coordinates: 2852249..2853511 (+)
• Length: 420 a.a.
• NCBI ID: WP_010948208.1
• Uniprot ID: Q5ZSL1
• Organism: Legionella pneumophila strain E7_O
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2847249..2858511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9E94_RS12650 (A9E94_12650)	-	2847507..2847827 (-)	321	WP_010948205.1	hypothetical protein	-
A9E94_RS12655 (A9E94_12655)	ceg32	2848135..2850963 (+)	2829	WP_010948206.1	Dot/Icm T4SS effector Ceg32/SidI	-
A9E94_RS12660 (A9E94_12660)	mesI	2850965..2851852 (+)	888	WP_010948207.1	Dot/Icm T4SS metaeffector MesI	-
A9E94_RS12665 (A9E94_12665)	lqsT	2852249..2853511 (+)	1263	WP_010948208.1	HAMP domain-containing sensor histidine kinase	Regulator
A9E94_RS12670 (A9E94_12670)	-	2853559..2854254 (-)	696	WP_010948209.1	iron-containing redox enzyme family protein	-
A9E94_RS12675 (A9E94_12675)	sdjA	2854653..2857076 (-)	2424	WP_010948210.1	Dot/Icm T4SS effector SdjA	-
A9E94_RS12680 (A9E94_12680)	dupB	2857147..2858340 (-)	1194	WP_010948211.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48657.07 Da
• Isoelectric Point: 7.9744

>NTDB_id=184654 A9E94_RS12665 WP_010948208.1 2852249..2853511(+) (lqsT) [Legionella pneumophila strain E7_O]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALILLISGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFSIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKEGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=184654 A9E94_RS12665 WP_010948208.1 2852249..2853511(+) (lqsT) [Legionella pneumophila strain E7_O]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTCTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTGCCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCGACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTTTCCAGTGTATTGGGGGCTCTTATAT
TACTTATATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGTGCCTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCCGAATTACAGGAATTGATTGTCGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGCATAGAAATGAGTAATCAATTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTTCGATTTATTCCATCAAAAAATTGCTCAAGGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGTCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGAAGGAACTGGTTTAGGCTTGGCCTATTGTAAACTTCTGATGCAAGCAGCAGGCGGTGATATT
TCCTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5ZSL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	100	100	1