Detailed information NTG0184319

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A9E86_RS12860
• Genome accession: NZ_CP015944
• Coordinates: 2899476..2900561 (+)
• Length: 361 a.a.
• NCBI ID: WP_010948297.1
• Uniprot ID: A0AAN5SZF3
• Organism: Legionella pneumophila strain C10_S
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2894476..2905561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9E86_RS12835 (A9E86_12835)	-	2894869..2895618 (-)	750	WP_010948292.1	CPBP family glutamic-type intramembrane protease	-
A9E86_RS12840 (A9E86_12840)	rsmB	2895615..2896898 (-)	1284	WP_010948293.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
A9E86_RS12845 (A9E86_12845)	fmt	2896895..2897839 (-)	945	WP_010948294.1	methionyl-tRNA formyltransferase	-
A9E86_RS12850 (A9E86_12850)	def	2897836..2898348 (-)	513	WP_010948295.1	peptide deformylase	-
A9E86_RS12855 (A9E86_12855)	-	2898442..2899479 (+)	1038	WP_010948296.1	LysM domain-containing protein	-
A9E86_RS12860 (A9E86_12860)	dprA	2899476..2900561 (+)	1086	WP_010948297.1	DNA-processing protein DprA	Machinery gene
A9E86_RS12865 (A9E86_12865)	-	2900551..2900988 (+)	438	WP_015444006.1	DUF494 family protein	-
A9E86_RS12870 (A9E86_12870)	topA	2901067..2903346 (+)	2280	WP_010948299.1	type I DNA topoisomerase	-
A9E86_RS12875 (A9E86_12875)	-	2903448..2905421 (-)	1974	WP_010948300.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39545.75 Da
• Isoelectric Point: 7.5076

>NTDB_id=184319 A9E86_RS12860 WP_010948297.1 2899476..2900561(+) (dprA) [Legionella pneumophila strain C10_S]
MNNLQPLLALNRMKKIGPRTVLKLQKRWPDLNLMFQLSNVDLEEAGLPSWLAQTIKNFDPGFIKTDLNWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSAMTQPNLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEGGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=184319 A9E86_RS12860 WP_010948297.1 2899476..2900561(+) (dprA) [Legionella pneumophila strain C10_S]
ATGAATAATCTGCAACCCCTCCTCGCCTTAAACAGGATGAAAAAAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCAAATGTTGATCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGCACAAA
CCATAAAAAATTTTGATCCGGGCTTTATAAAAACTGATTTGAACTGGTTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCCGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCCATGACACAACCCAACCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGCGCATTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCTTTGGGAATTGATGCTCATGCTCATTTAGGCTGT
CTGGAAGGAGGCGGCAAAACGATAGCGGTCTTAGGTACCGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCTATTCCCGGATCAATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAACAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATCGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACGACTATC
GATCAAATCATTGATCGTAGCGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATGGCAGTGCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	98.338	100	0.983
dprA	Vibrio cholerae strain A1552	42.781	100	0.443
dprA	Vibrio campbellii strain DS40M4	44.444	99.723	0.443
dprA	Glaesserella parasuis strain SC1401	38.933	100	0.404
dprA	Haemophilus influenzae Rd KW20	46.048	80.609	0.371