Detailed information NTG0183763

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: BS21228_RS12820
• Genome accession: NZ_CP020023
• Coordinates: 2386509..2387591 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain ATCC 21228
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2381509..2392591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BS21228_RS12805 (BS21228_12760)	mcsB	2381517..2382608 (+)	1092	WP_003235007.1	protein arginine kinase	-
BS21228_RS12810 (BS21228_12765)	clpC	2382605..2385037 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
BS21228_RS12815 (BS21228_12770)	radA/sms	2385129..2386505 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
BS21228_RS12820 (BS21228_12775)	disA	2386509..2387591 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
BS21228_RS12825 (BS21228_12780)	yacL	2387707..2388807 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
BS21228_RS12830 (BS21228_12785)	ispD	2388822..2389520 (+)	699	WP_014478616.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
BS21228_RS12835 (BS21228_12790)	ispF	2389513..2389989 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
BS21228_RS12840 (BS21228_12795)	gltX	2390080..2391531 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
BS21228_RS12850 (BS21228_12805)	cysE	2391833..2392486 (+)	654	WP_014478618.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=183763 BS21228_RS12820 WP_003225736.1 2386509..2387591(+) (disA) [Bacillus subtilis strain ATCC 21228]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=183763 BS21228_RS12820 WP_003225736.1 2386509..2387591(+) (disA) [Bacillus subtilis strain ATCC 21228]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1