Detailed information NTG0183438

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLJM4_RS11690
• Genome accession: NZ_CP015909
• Coordinates: 2274917..2275948 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain JM4
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2269917..2280948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLJM4_RS11665 (LLJM4_2265)	-	2271120..2271617 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLJM4_RS11670 (LLJM4_2266)	-	2271604..2271813 (-)	210	WP_011677212.1	hypothetical protein	-
LLJM4_RS11675 (LLJM4_2268)	-	2272101..2272991 (+)	891	WP_015082326.1	IS982-like element IS982B family transposase	-
LLJM4_RS11680 (LLJM4_2269)	kwcM	2273098..2274417 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
LLJM4_RS11685 (LLJM4_2270)	-	2274485..2274598 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLJM4_RS11690 (LLJM4_2271)	sepM	2274917..2275948 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLJM4_RS11695 (LLJM4_2272)	coaD	2275932..2276432 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLJM4_RS11700 (LLJM4_2273)	rsmD	2276480..2277019 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLJM4_RS11705 (LLJM4_2274)	-	2277190..2278410 (-)	1221	WP_134047487.1	MFS transporter	-
LLJM4_RS11710 (LLJM4_2275)	lmrP	2278494..2279720 (-)	1227	Protein_2279	multidrug efflux MFS transporter LmrP	-
LLJM4_RS11715 (LLJM4_2276)	-	2279908..2280402 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=183438 LLJM4_RS11690 WP_011677213.1 2274917..2275948(-) (sepM) [Lactococcus cremoris strain JM4]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=183438 LLJM4_RS11690 WP_011677213.1 2274917..2275948(-) (sepM) [Lactococcus cremoris strain JM4]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49