Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLJM4_RS04250 Genome accession   NZ_CP015909
Coordinates   846175..847647 (+) Length   490 a.a.
NCBI ID   WP_081196783.1    Uniprot ID   -
Organism   Lactococcus cremoris strain JM4     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 841175..852647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLJM4_RS04220 (LLJM4_1549) - 841642..842478 (+) 837 WP_021165524.1 metallophosphoesterase -
  LLJM4_RS04225 (LLJM4_1548) - 842571..843482 (+) 912 Protein_824 CHAP domain-containing protein -
  LLJM4_RS04230 (LLJM4_1547) - 843719..844081 (+) 363 Protein_825 TIGR02328 family protein -
  LLJM4_RS04235 (LLJM4_1546) - 844405..844650 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLJM4_RS04240 (LLJM4_1545) - 844783..845313 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLJM4_RS04245 (LLJM4_1544) covR 845470..846162 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLJM4_RS04250 (LLJM4_1543) covS 846175..847647 (+) 1473 WP_081196783.1 HAMP domain-containing histidine kinase Regulator
  LLJM4_RS04255 (LLJM4_1542) - 847833..849074 (+) 1242 WP_015082643.1 ammonium transporter -
  LLJM4_RS04260 (LLJM4_1541) - 849159..849500 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLJM4_RS04265 (LLJM4_1540) murD 849669..851018 (+) 1350 WP_021211936.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLJM4_RS04270 (LLJM4_1539) murG 851261..852334 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55905.78 Da        Isoelectric Point: 4.7018

>NTDB_id=183413 LLJM4_RS04250 WP_081196783.1 846175..847647(+) (covS) [Lactococcus cremoris strain JM4]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=183413 LLJM4_RS04250 WP_081196783.1 846175..847647(+) (covS) [Lactococcus cremoris strain JM4]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAATCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.898

100

0.949

Multiple sequence alignment