Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLUC08_RS10995 Genome accession   NZ_CP015903
Coordinates   2239431..2240459 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis subsp. lactis strain UC08     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2234431..2245459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC08_RS10975 (LLUC08_2125) - 2235505..2236362 (-) 858 WP_058203259.1 Rgg/GadR/MutR family transcriptional regulator -
  LLUC08_RS10980 (LLUC08_2126) - 2236473..2237612 (-) 1140 WP_012898644.1 MFS transporter -
  LLUC08_RS10985 (LLUC08_2127) kwcM 2237609..2238928 (-) 1320 WP_058207975.1 KxxxW cyclic peptide radical SAM maturase -
  LLUC08_RS10990 (LLUC08_2128) - 2238996..2239109 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  LLUC08_RS10995 (LLUC08_2129) sepM 2239431..2240459 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  LLUC08_RS11000 (LLUC08_2130) coaD 2240446..2240943 (-) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  LLUC08_RS11005 (LLUC08_2131) rsmD 2240991..2241530 (-) 540 WP_162498911.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LLUC08_RS11010 (LLUC08_2132) - 2241701..2242921 (-) 1221 WP_081200148.1 MFS transporter -
  LLUC08_RS11015 (LLUC08_2133) lmrP 2243005..2244231 (-) 1227 WP_012898648.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=183152 LLUC08_RS10995 WP_003132657.1 2239431..2240459(-) (sepM) [Lactococcus lactis subsp. lactis strain UC08]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=183152 LLUC08_RS10995 WP_003132657.1 2239431..2240459(-) (sepM) [Lactococcus lactis subsp. lactis strain UC08]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AAGTCTTCTTAGTGCCTGATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491

Multiple sequence alignment