Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLUC06_RS12250 Genome accession   NZ_CP015902
Coordinates   2448312..2449340 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis subsp. lactis strain UC06     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2443312..2454340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC06_RS12230 (LLUC06_2375) - 2444387..2445244 (-) 858 WP_081213766.1 Rgg/GadR/MutR family transcriptional regulator -
  LLUC06_RS12235 (LLUC06_2376) - 2445354..2446493 (-) 1140 WP_012898644.1 MFS transporter -
  LLUC06_RS12240 (LLUC06_2377) kwcM 2446496..2447809 (-) 1314 WP_058203260.1 KxxxW cyclic peptide radical SAM maturase -
  LLUC06_RS12245 (LLUC06_2378) - 2447877..2447990 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  LLUC06_RS12250 (LLUC06_2379) sepM 2448312..2449340 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  LLUC06_RS12255 (LLUC06_2380) coaD 2449327..2449824 (-) 498 WP_081213767.1 pantetheine-phosphate adenylyltransferase -
  LLUC06_RS12260 (LLUC06_2381) rsmD 2449872..2450411 (-) 540 WP_015427191.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LLUC06_RS12265 (LLUC06_2382) - 2450582..2451802 (-) 1221 WP_012898647.1 MFS transporter -
  LLUC06_RS12270 (LLUC06_2383) lmrP 2451885..2453111 (-) 1227 WP_081213768.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=183102 LLUC06_RS12250 WP_003132657.1 2448312..2449340(-) (sepM) [Lactococcus lactis subsp. lactis strain UC06]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=183102 LLUC06_RS12250 WP_003132657.1 2448312..2449340(-) (sepM) [Lactococcus lactis subsp. lactis strain UC06]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTATAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATAGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AAGTCTTCTTAGTGCCTGATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491

Multiple sequence alignment