Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   LLUC06_RS03695 Genome accession   NZ_CP015902
Coordinates   703688..706138 (+) Length   816 a.a.
NCBI ID   WP_058220629.1    Uniprot ID   A0A1V0P0K8
Organism   Lactococcus lactis subsp. lactis strain UC06     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 698688..711138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC06_RS03670 (LLUC06_0698) - 699452..699964 (+) 513 WP_012897343.1 adenine phosphoribosyltransferase -
  LLUC06_RS03675 (LLUC06_0699) rpoE 700181..700744 (+) 564 WP_012897344.1 DNA-directed RNA polymerase subunit delta -
  LLUC06_RS03680 (LLUC06_0700) mltG 700881..702533 (+) 1653 WP_058220628.1 endolytic transglycosylase MltG -
  LLUC06_RS03685 (LLUC06_0701) greA 702593..703066 (+) 474 WP_033899645.1 transcription elongation factor GreA -
  LLUC06_RS03690 (LLUC06_0702) - 703243..703698 (+) 456 WP_010905471.1 CtsR family transcriptional regulator -
  LLUC06_RS03695 (LLUC06_0703) clpC 703688..706138 (+) 2451 WP_058220629.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  LLUC06_RS03700 (LLUC06_0704) hpf 706273..706830 (+) 558 WP_003129564.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LLUC06_RS03705 (LLUC06_0705) eno 707015..708316 (+) 1302 WP_010905473.1 surface-displayed alpha-enolase -
  LLUC06_RS03710 (LLUC06_0706) - 708431..709102 (-) 672 WP_017864216.1 ABC transporter ATP-binding protein -
  LLUC06_RS03715 (LLUC06_0707) - 709105..710178 (-) 1074 WP_058221033.1 ABC transporter permease -
  LLUC06_RS03720 (LLUC06_0708) - 710190..710759 (-) 570 WP_081213416.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90393.76 Da        Isoelectric Point: 6.5300

>NTDB_id=183064 LLUC06_RS03695 WP_058220629.1 703688..706138(+) (clpC) [Lactococcus lactis subsp. lactis strain UC06]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKVAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEALAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=183064 LLUC06_RS03695 WP_058220629.1 703688..706138(+) (clpC) [Lactococcus lactis subsp. lactis strain UC06]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGGTGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGCTTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTTGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAAGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(357-453)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(19-69)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(96-144)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)

ATPase family associated with various cellular activities (AAA) (AAA)

(218-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0P0K8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

99.755

100

0.998
  clpC Streptococcus thermophilus LMD-9

50.421

100

0.513
  clpC Streptococcus thermophilus LMG 18311

50.301

100

0.512
  clpC Streptococcus pneumoniae Rx1

49.216

100

0.5
  clpC Streptococcus pneumoniae D39

49.216

100

0.5
  clpC Streptococcus pneumoniae TIGR4

49.095

100

0.499
  clpC Streptococcus mutans UA159

48.558

100

0.495
  clpC Bacillus subtilis subsp. subtilis str. 168

50.374

98.284

0.495
  clpE Streptococcus mutans UA159

47.692

79.657

0.38
  clpC Lactococcus lactis subsp. cremoris KW2

46.87

80.27

0.376
  clpE Streptococcus pneumoniae TIGR4

47.528

76.838

0.365
  clpE Streptococcus pneumoniae Rx1

47.528

76.838

0.365
  clpE Streptococcus pneumoniae D39

47.528

76.838

0.365
  clpE Streptococcus pneumoniae R6

47.528

76.838

0.365

Multiple sequence alignment