Detailed information NTG0182957

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLJM1_RS11670
• Genome accession: NZ_CP015899
• Coordinates: 2249468..2250499 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain JM1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2244468..2255499

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLJM1_RS11645 (LLJM1_2251)	-	2245673..2246170 (-)	498	WP_032951474.1	nitroreductase family protein	-
LLJM1_RS11650 (LLJM1_2252)	-	2246157..2246366 (-)	210	WP_011677212.1	hypothetical protein	-
LLJM1_RS11655 (LLJM1_2253)	-	2246653..2247543 (+)	891	WP_081196119.1	IS982-like element IS982B family transposase	-
LLJM1_RS11660 (LLJM1_2254)	kwcM	2247650..2248969 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
LLJM1_RS11665 (LLJM1_2255)	-	2249037..2249150 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLJM1_RS11670 (LLJM1_2256)	sepM	2249468..2250499 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLJM1_RS11675 (LLJM1_2257)	coaD	2250483..2250983 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLJM1_RS11680 (LLJM1_2258)	rsmD	2251031..2251570 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLJM1_RS11685 (LLJM1_2259)	-	2251741..2252961 (-)	1221	WP_011677216.1	MFS transporter	-
LLJM1_RS11690 (LLJM1_2260)	lmrP	2253045..2254274 (-)	1230	Protein_2273	multidrug efflux MFS transporter LmrP	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=182957 LLJM1_RS11670 WP_011677213.1 2249468..2250499(-) (sepM) [Lactococcus cremoris strain JM1]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=182957 LLJM1_RS11670 WP_011677213.1 2249468..2250499(-) (sepM) [Lactococcus cremoris strain JM1]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTATTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49