Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLJM1_RS03905 Genome accession   NZ_CP015899
Coordinates   705042..706514 (+) Length   490 a.a.
NCBI ID   WP_032950293.1    Uniprot ID   A0A1V0PFR7
Organism   Lactococcus cremoris strain JM1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 700042..711514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLJM1_RS03875 (LLJM1_0719) - 700485..701333 (+) 849 WP_231099822.1 CHAP domain-containing protein -
  LLJM1_RS03880 (LLJM1_03245) - 701570..701932 (+) 363 Protein_727 TIGR02328 family protein -
  LLJM1_RS03885 (LLJM1_0721) - 702256..702501 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLJM1_RS03890 (LLJM1_03250) - 702606..703496 (-) 891 WP_308781426.1 IS982 family transposase -
  LLJM1_RS03895 (LLJM1_0724) - 703650..704180 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLJM1_RS03900 (LLJM1_0725) covR 704337..705029 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLJM1_RS03905 (LLJM1_0726) covS 705042..706514 (+) 1473 WP_032950293.1 HAMP domain-containing histidine kinase Regulator
  LLJM1_RS03910 (LLJM1_0727) - 706700..707941 (+) 1242 WP_015082643.1 ammonium transporter -
  LLJM1_RS03915 (LLJM1_0728) - 708025..708366 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLJM1_RS03920 (LLJM1_0729) murD 708535..709884 (+) 1350 WP_032950291.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLJM1_RS03925 (LLJM1_0730) murG 710127..711200 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55890.81 Da        Isoelectric Point: 4.7784

>NTDB_id=182929 LLJM1_RS03905 WP_032950293.1 705042..706514(+) (covS) [Lactococcus cremoris strain JM1]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAKEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=182929 LLJM1_RS03905 WP_032950293.1 705042..706514(+) (covS) [Lactococcus cremoris strain JM1]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCAAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0PFR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment