Detailed information NTG0182872

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: B2G84_RS04150
• Genome accession: NZ_CP019979
• Coordinates: 741904..742689 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain Sag158
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 736904..747689

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B2G84_RS11050	-	738021..738464 (+)	444	WP_001048166.1	hypothetical protein	-
B2G84_RS11055	-	738549..738815 (+)	267	WP_001865676.1	hypothetical protein	-
B2G84_RS11060	-	738916..739044 (+)	129	WP_000962057.1	hypothetical protein	-
B2G84_RS11065	-	739053..739373 (+)	321	WP_001865677.1	hypothetical protein	-
B2G84_RS04140 (B2G84_04140)	-	739470..740141 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
B2G84_RS04145 (B2G84_04145)	-	740198..741643 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
B2G84_RS04150 (B2G84_04150)	endA	741904..742689 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
B2G84_RS04155 (B2G84_04155)	-	742767..743405 (-)	639	WP_000478529.1	VTT domain-containing protein	-
B2G84_RS04160 (B2G84_04160)	-	743622..744278 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
B2G84_RS04165 (B2G84_04165)	-	744275..745048 (+)	774	WP_000012390.1	ABC transporter permease	-
B2G84_RS04170 (B2G84_04170)	-	745212..746030 (+)	819	WP_000601007.1	hypothetical protein	-
B2G84_RS04175 (B2G84_04175)	-	746067..746951 (-)	885	WP_079218662.1	LysR family transcriptional regulator	-
B2G84_RS04180 (B2G84_04180)	-	747144..747650 (+)	507	Protein_742	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=182872 B2G84_RS04150 WP_000825431.1 741904..742689(+) (endA) [Streptococcus agalactiae strain Sag158]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=182872 B2G84_RS04150 WP_000825431.1 741904..742689(+) (endA) [Streptococcus agalactiae strain Sag158]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391