Detailed information NTG0182822

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LL158_RS03305
• Genome accession: NZ_CP015894
• Coordinates: 631053..633503 (+)
• Length: 816 a.a.
• NCBI ID: WP_015082152.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain 158
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	627935..630323	631053..633503	flank	730

Gene organization within MGE regions

Location: 627935..633503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL158_RS03300 (LL158_0617)	-	630608..631063 (+)	456	WP_011834627.1	CtsR family transcriptional regulator	-
LL158_RS03305 (LL158_0618)	clpC	631053..633503 (+)	2451	WP_015082152.1	ATP-dependent Clp protease ATP-binding subunit	Regulator

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90308.67 Da
• Isoelectric Point: 6.5301

>NTDB_id=182822 LL158_RS03305 WP_015082152.1 631053..633503(+) (clpC) [Lactococcus cremoris strain 158]
MKFENVKYTPTLDRIFEKAAEDAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEVVGTEHLLYALLQVEDGFGIQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPISK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=182822 LL158_RS03305 WP_015082152.1 631053..633503(+) (clpC) [Lactococcus cremoris strain 158]
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAGAAAGCAGCAGAAGATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTCACTGTAGCTAGCTTTTTAGCTGTTCATAATAATGCAGAAGTAGTAGGAAC
GGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTATTCAACTTTTGAAGTTACAAAAAATCAATATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATTTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGCGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCCCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGATTTTCAAATGGTTGGGGCAACGACTTATCACGAATACCAAAAATACATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCCATTGCTATCCTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCTGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATCGACTTGCTTGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAACTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAATTTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTTGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGATATGAGTGAATTTAT
GGAAAAACATTCAACTTCACGATTGATTGGAGCACCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GTGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCCTGACGTTTTCAATATCATGTTG
CAAATTCTAGATGATGGATTTGTGACAGATACAAAGGGTCGCAAAGTTGATTTTAGAAACACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCAGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAGCAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-449)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (23-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	95.588	100	0.956
clpC	Streptococcus thermophilus LMD-9	51.023	100	0.52
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus pneumoniae Rx1	49.638	100	0.504
clpC	Streptococcus pneumoniae D39	49.638	100	0.504
clpC	Streptococcus pneumoniae TIGR4	49.517	100	0.502
clpC	Streptococcus mutans UA159	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.249	98.284	0.494
clpE	Streptococcus mutans UA159	46.923	79.657	0.374
clpC	Lactococcus lactis subsp. cremoris KW2	46.626	79.902	0.373
clpE	Streptococcus pneumoniae TIGR4	47.049	76.838	0.362
clpE	Streptococcus pneumoniae Rx1	47.049	76.838	0.362
clpE	Streptococcus pneumoniae D39	47.049	76.838	0.362
clpE	Streptococcus pneumoniae R6	47.049	76.838	0.362