Detailed information NTG0182202

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: A8C77_RS22675
• Genome accession: NZ_CP015779
• Coordinates: 4008951..4009745 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain Tangail-1
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4003951..4014745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A8C77_RS22655 (A8C77_21315)	-	4005752..4005985 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
A8C77_RS22660 (A8C77_21320)	-	4006034..4006762 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
A8C77_RS22665 (A8C77_21325)	-	4006813..4006959 (+)	147	WP_001247671.1	YycC family protein	-
A8C77_RS22670 (A8C77_21330)	-	4007127..4008653 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
A8C77_RS22675 (A8C77_21335)	spo0A	4008951..4009745 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
A8C77_RS22685 (A8C77_21345)	spoIVB	4010033..4011331 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
A8C77_RS22690 (A8C77_21350)	recN	4011450..4013189 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
A8C77_RS22695 (A8C77_21355)	argR	4013457..4013906 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=182202 A8C77_RS22675 WP_003161566.1 4008951..4009745(-) (spo0A) [Bacillus anthracis strain Tangail-1]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=182202 A8C77_RS22675 WP_003161566.1 4008951..4009745(-) (spo0A) [Bacillus anthracis strain Tangail-1]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818