Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A7327_RS10875 Genome accession   NZ_CP015646
Coordinates   2172605..2173321 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 08-02300     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2167605..2178321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7327_RS10845 (A7327_10840) - 2167825..2168451 (+) 627 WP_000522384.1 nitroreductase family protein -
  A7327_RS10850 (A7327_10845) - 2168812..2169597 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  A7327_RS14795 hld 2170193..2170273 (-) 81 WP_000046022.1 delta-hemolysin -
  A7327_RS10860 (A7327_10855) agrB 2170563..2171132 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  A7327_RS10865 (A7327_10860) agrD 2171129..2171269 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  A7327_RS10870 (A7327_10865) agrC 2171294..2172586 (+) 1293 WP_064626826.1 quorum-sensing sensor histidine kinase AgrC -
  A7327_RS10875 (A7327_10870) agrA 2172605..2173321 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  A7327_RS10880 (A7327_10875) - 2173393..2173502 (+) 110 Protein_2068 hypothetical protein -
  A7327_RS10885 (A7327_10880) - 2173690..2174649 (-) 960 WP_001253310.1 carbohydrate kinase family protein -
  A7327_RS10890 (A7327_10885) - 2174646..2176130 (-) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  A7327_RS10895 (A7327_10890) - 2176279..2177229 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=181775 A7327_RS10875 WP_000688498.1 2172605..2173321(+) (agrA) [Staphylococcus aureus strain 08-02300]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=181775 A7327_RS10875 WP_000688498.1 2172605..2173321(+) (agrA) [Staphylococcus aureus strain 08-02300]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment