Detailed information NTG0181737

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7327_RS00220
• Genome accession: NZ_CP015646
• Coordinates: 40755..41642 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 08-02300
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 35755..46642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7327_RS00185 (A7327_00185)	-	35783..35866 (+)	84	WP_031797553.1	hypothetical protein	-
A7327_RS00190 (A7327_00190)	-	35974..36471 (-)	498	WP_001065268.1	glutathione peroxidase	-
A7327_RS00195 (A7327_00195)	-	36481..36741 (-)	261	WP_001789307.1	hypothetical protein	-
A7327_RS00200 (A7327_00200)	-	37123..37236 (-)	114	WP_011447078.1	hypothetical protein	-
A7327_RS00210 (A7327_00210)	-	37895..39895 (-)	2001	WP_000776733.1	ABC transporter permease	-
A7327_RS00215 (A7327_00215)	-	39892..40647 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7327_RS00220 (A7327_00220)	braS	40755..41642 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7327_RS00225 (A7327_00225)	braR	41653..42318 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7327_RS00230 (A7327_00230)	-	42344..42544 (-)	201	WP_000604727.1	hypothetical protein	-
A7327_RS00240 (A7327_00240)	-	42742..44166 (+)	1425	WP_000953744.1	alkaline phosphatase	-
A7327_RS14785	-	44226..44327 (-)	102	WP_000731972.1	SE2200 family small protein	-
A7327_RS00250 (A7327_00245)	-	44449..44904 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7327_RS00255 (A7327_00250)	-	45149..45910 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=181737 A7327_RS00220 WP_000143419.1 40755..41642(-) (braS) [Staphylococcus aureus strain 08-02300]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=181737 A7327_RS00220 WP_000143419.1 40755..41642(-) (braS) [Staphylococcus aureus strain 08-02300]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997