Detailed information NTG0181736

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7P66_RS11570
• Genome accession: NZ_CP015645
• Coordinates: 2293538..2294425 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 08-02119
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2288538..2299425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7P66_RS11535 (A7P66_11535)	-	2289270..2290031 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
A7P66_RS11540 (A7P66_11540)	-	2290276..2290731 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7P66_RS15150	-	2290853..2290954 (+)	102	WP_000731972.1	SE2200 family small protein	-
A7P66_RS11550 (A7P66_11545)	-	2291014..2292438 (-)	1425	WP_000953748.1	alkaline phosphatase	-
A7P66_RS11560 (A7P66_11555)	-	2292636..2292836 (+)	201	WP_000604727.1	hypothetical protein	-
A7P66_RS11565 (A7P66_11560)	braR	2292862..2293527 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7P66_RS11570 (A7P66_11565)	braS	2293538..2294425 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7P66_RS11575 (A7P66_11570)	-	2294533..2295288 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7P66_RS11580 (A7P66_11575)	-	2295285..2297285 (+)	2001	WP_000776740.1	ABC transporter permease	-
A7P66_RS11590 (A7P66_11585)	-	2297944..2298057 (+)	114	Protein_2213	hypothetical protein	-
A7P66_RS11595 (A7P66_11590)	-	2298439..2298699 (+)	261	WP_001791974.1	hypothetical protein	-
A7P66_RS11600 (A7P66_11595)	-	2298709..2299206 (+)	498	WP_001065268.1	glutathione peroxidase	-
A7P66_RS11605 (A7P66_11600)	-	2299314..2299406 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=181736 A7P66_RS11570 WP_000143417.1 2293538..2294425(+) (braS) [Staphylococcus aureus strain 08-02119]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=181736 A7P66_RS11570 WP_000143417.1 2293538..2294425(+) (braS) [Staphylococcus aureus strain 08-02119]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99