Detailed information NTG0181672

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A7X73_RS05010
• Genome accession: NZ_CP015642
• Coordinates: 1093629..1094672 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain MR1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1088629..1099672

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7X73_RS04985 (A7X73_04945)	-	1089632..1090351 (+)	720	WP_105966989.1	type 1 glutamine amidotransferase	-
A7X73_RS04990 (A7X73_04950)	-	1090434..1091420 (-)	987	WP_002481667.1	FUSC family protein	-
A7X73_RS04995 (A7X73_04955)	map	1091640..1092404 (+)	765	WP_060803962.1	type I methionyl aminopeptidase	-
A7X73_RS05000 (A7X73_04960)	-	1092520..1092915 (+)	396	WP_002481665.1	hypothetical protein	-
A7X73_RS05005 (A7X73_04965)	liaF	1092931..1093632 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
A7X73_RS05010 (A7X73_04970)	vraS	1093629..1094672 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
A7X73_RS05015 (A7X73_04975)	vraR	1094662..1095291 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
A7X73_RS05020 (A7X73_04980)	-	1095362..1095940 (-)	579	WP_002481661.1	beta-class carbonic anhydrase	-
A7X73_RS05025 (A7X73_04985)	-	1096148..1097224 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
A7X73_RS05030 (A7X73_04990)	-	1097355..1097645 (-)	291	WP_002481659.1	hypothetical protein	-
A7X73_RS05035 (A7X73_04995)	-	1097653..1098117 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
A7X73_RS05040 (A7X73_05000)	-	1098341..1098547 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=181672 A7X73_RS05010 WP_002481663.1 1093629..1094672(+) (vraS) [Staphylococcus simulans strain MR1]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=181672 A7X73_RS05010 WP_002481663.1 1093629..1094672(+) (vraS) [Staphylococcus simulans strain MR1]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTATACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862