Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A7X73_RS04620 Genome accession   NZ_CP015642
Coordinates   1018802..1019518 (-) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain MR1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1013802..1024518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7X73_RS04600 (A7X73_04575) - 1014947..1015588 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  A7X73_RS04605 (A7X73_04580) - 1015639..1015863 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  A7X73_RS04610 (A7X73_04585) - 1015919..1017007 (-) 1089 WP_070463416.1 YeeE/YedE family protein -
  A7X73_RS04615 (A7X73_04590) - 1017243..1018727 (+) 1485 WP_105967007.1 GH32 C-terminal domain-containing protein -
  A7X73_RS04620 (A7X73_04595) agrA 1018802..1019518 (-) 717 WP_002481723.1 quorum-sensing response regulator AgrA Regulator
  A7X73_RS14190 (A7X73_04600) agrC 1019521..1020822 (-) 1302 WP_105967006.1 quorum-sensing sensor histidine kinase AgrC -
  A7X73_RS04630 (A7X73_04605) agrD 1020862..1020999 (-) 138 WP_023015908.1 cyclic lactone autoinducer peptide AgrD -
  A7X73_RS04635 (A7X73_04610) - 1020999..1021577 (-) 579 WP_002481720.1 accessory gene regulator AgrB -
  A7X73_RS14195 - 1021973..1022053 (+) 81 WP_411756594.1 delta-lysin family phenol-soluble modulin -
  A7X73_RS04645 (A7X73_04615) - 1022358..1023158 (-) 801 WP_105967004.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=181671 A7X73_RS04620 WP_002481723.1 1018802..1019518(-) (agrA) [Staphylococcus simulans strain MR1]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=181671 A7X73_RS04620 WP_002481723.1 1018802..1019518(-) (agrA) [Staphylococcus simulans strain MR1]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTTATG
TTCTTTGAATCCTCGGCAAAATCACATCGTTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794

Multiple sequence alignment