Detailed information NTG0180641

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A2I68_RS07955
• Genome accession: NZ_CP015553
• Coordinates: 1541310..1542353 (-)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain TMW 2.1596
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1536310..1547353

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2I68_RS07925 (A2I68_07765)	-	1537448..1537654 (-)	207	WP_015900698.1	DUF1128 family protein	-
A2I68_RS07930 (A2I68_07770)	-	1537890..1538354 (+)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
A2I68_RS07935 (A2I68_07775)	-	1538362..1538658 (+)	297	WP_015900700.1	hypothetical protein	-
A2I68_RS07940 (A2I68_07780)	-	1538777..1539853 (+)	1077	WP_046100413.1	YihY/virulence factor BrkB family protein	-
A2I68_RS07945 (A2I68_07785)	-	1540063..1540641 (+)	579	WP_015900702.1	carbonic anhydrase	-
A2I68_RS07950 (A2I68_07790)	vraR	1540691..1541320 (-)	630	WP_046100412.1	response regulator transcription factor	Regulator
A2I68_RS07955 (A2I68_07795)	vraS	1541310..1542353 (-)	1044	WP_015900704.1	sensor histidine kinase	Regulator
A2I68_RS07960 (A2I68_07800)	liaF	1542350..1543051 (-)	702	WP_046100411.1	cell wall-active antibiotics response protein LiaF	-
A2I68_RS07965 (A2I68_07805)	-	1543067..1543462 (-)	396	WP_015900706.1	hypothetical protein	-
A2I68_RS07970 (A2I68_07810)	map	1543596..1544363 (-)	768	WP_015900707.1	type I methionyl aminopeptidase	-
A2I68_RS07975 (A2I68_07815)	-	1544615..1545601 (+)	987	WP_046100410.1	aromatic acid exporter family protein	-
A2I68_RS07980 (A2I68_07820)	-	1545651..1546376 (-)	726	WP_046100409.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=180641 A2I68_RS07955 WP_015900704.1 1541310..1542353(-) (vraS) [Staphylococcus carnosus strain TMW 2.1596]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180641 A2I68_RS07955 WP_015900704.1 1541310..1542353(-) (vraS) [Staphylococcus carnosus strain TMW 2.1596]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847