Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV/pilI   Type   Regulator
Locus tag   BZG33_RS03330 Genome accession   NZ_CP019466
Coordinates   563408..564022 (+) Length   204 a.a.
NCBI ID   WP_012503479.1    Uniprot ID   B4RKG4
Organism   Neisseria gonorrhoeae strain RIVM0610     
Function   repress natural transformation; antagonize ComP (predicted from homology)   
Competence regulation

Genomic Context

Location: 558408..569022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG33_RS03295 (BZG33_03235) - 558906..559238 (+) 333 WP_003687908.1 hypothetical protein -
  BZG33_RS03300 (BZG33_03240) - 559568..560077 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  BZG33_RS03310 (BZG33_03250) - 560309..560890 (-) 582 WP_003690895.1 superoxide dismutase -
  BZG33_RS03320 (BZG33_03260) dnaB 561054..562457 (+) 1404 WP_012503477.1 replicative DNA helicase -
  BZG33_RS03325 (BZG33_03265) pilH 562714..563376 (+) 663 WP_047916986.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  BZG33_RS03330 (BZG33_03270) pilV/pilI 563408..564022 (+) 615 WP_012503479.1 type IV pilus modification protein PilV Regulator
  BZG33_RS03335 (BZG33_03275) pilJ 564019..564981 (+) 963 WP_047921846.1 PilW family protein Machinery gene
  BZG33_RS03340 (BZG33_03280) pilK 564960..565568 (+) 609 WP_047921847.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  BZG33_RS03345 (BZG33_03285) pilL 565570..566043 (+) 474 WP_012503482.1 PilX family type IV pilin Machinery gene
  BZG33_RS03350 (BZG33_03290) - 566113..566421 (-) 309 WP_003706588.1 AzlD family protein -
  BZG33_RS03355 (BZG33_03295) - 566418..567129 (-) 712 Protein_562 AzlC family ABC transporter permease -
  BZG33_RS03360 (BZG33_03300) dut 567295..567747 (+) 453 WP_003701071.1 dUTP diphosphatase -
  BZG33_RS03365 (BZG33_03305) dapC 567819..569006 (+) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 22099.99 Da        Isoelectric Point: 4.9673

>NTDB_id=180615 BZG33_RS03330 WP_012503479.1 563408..564022(+) (pilV/pilI) [Neisseria gonorrhoeae strain RIVM0610]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTGPYTPTPSGGDFKLNNNNLISKKDLAKAQLDRFDYELRNALPDAVAIHYAVCKDSSGGAPTLSGGTFSPNCDNKA
NGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGHE

Nucleotide


Download         Length: 615 bp        

>NTDB_id=180615 BZG33_RS03330 WP_012503479.1 563408..564022(+) (pilV/pilI) [Neisseria gonorrhoeae strain RIVM0610]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACGGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGGGCCGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGCTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGATTATGAATTGAGAAACGCCTTGCCGGATGCGGTAGCTATTCATT
ACGCCGTCTGCAAGGATTCGTCGGGTGGCGCGCCGACATTGTCCGGCGGTACTTTTTCTCCAAATTGCGATAATAAGGCA
AACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAGGT
GAGCGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCATGAATGA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RKG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV/pilI Neisseria gonorrhoeae MS11

90.686

100

0.907
  pilV Neisseria meningitidis 8013

84.135

100

0.858

Multiple sequence alignment