Detailed information NTG0180594

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A7E59_RS05120
• Genome accession: NZ_CP015552
• Coordinates: 1072730..1073773 (+)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain TMW 2.1538
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1067730..1078773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7E59_RS05095 (A7E59_04965)	-	1068707..1069432 (+)	726	WP_046100409.1	type 1 glutamine amidotransferase	-
A7E59_RS05100 (A7E59_04970)	-	1069482..1070468 (-)	987	WP_046100410.1	aromatic acid exporter family protein	-
A7E59_RS05105 (A7E59_04975)	map	1070720..1071487 (+)	768	WP_015900707.1	type I methionyl aminopeptidase	-
A7E59_RS05110 (A7E59_04980)	-	1071621..1072016 (+)	396	WP_015900706.1	hypothetical protein	-
A7E59_RS05115 (A7E59_04985)	liaF	1072032..1072733 (+)	702	WP_046100411.1	cell wall-active antibiotics response protein LiaF	-
A7E59_RS05120 (A7E59_04990)	vraS	1072730..1073773 (+)	1044	WP_015900704.1	sensor histidine kinase	Regulator
A7E59_RS05125 (A7E59_04995)	vraR	1073763..1074392 (+)	630	WP_046100412.1	response regulator transcription factor	Regulator
A7E59_RS05130 (A7E59_05000)	-	1074442..1075020 (-)	579	WP_015900702.1	carbonic anhydrase	-
A7E59_RS05135 (A7E59_05005)	-	1075230..1076306 (-)	1077	WP_046100413.1	YihY/virulence factor BrkB family protein	-
A7E59_RS05140 (A7E59_05010)	-	1076425..1076721 (-)	297	WP_015900700.1	hypothetical protein	-
A7E59_RS05145 (A7E59_05015)	-	1076729..1077193 (-)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
A7E59_RS05150 (A7E59_05020)	-	1077429..1077635 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=180594 A7E59_RS05120 WP_015900704.1 1072730..1073773(+) (vraS) [Staphylococcus carnosus strain TMW 2.1538]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180594 A7E59_RS05120 WP_015900704.1 1072730..1073773(+) (vraS) [Staphylococcus carnosus strain TMW 2.1538]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847