Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A2I63_RS04695 Genome accession   NZ_CP015536
Coordinates   1001280..1001996 (-) Length   238 a.a.
NCBI ID   WP_015900794.1    Uniprot ID   B9DMK5
Organism   Staphylococcus carnosus strain TMW 2.243     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 996280..1006996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2I63_RS04675 (A2I63_04580) - 997519..998163 (+) 645 WP_015900798.1 redox-sensing transcriptional repressor Rex -
  A2I63_RS04680 (A2I63_04585) - 998213..998437 (-) 225 WP_015900797.1 sulfurtransferase TusA family protein -
  A2I63_RS04685 (A2I63_04590) - 998464..999549 (-) 1086 WP_015900796.1 YeeE/YedE family protein -
  A2I63_RS04690 (A2I63_04595) - 999761..1001233 (+) 1473 WP_015900795.1 GH32 C-terminal domain-containing protein -
  A2I63_RS04695 (A2I63_04600) agrA 1001280..1001996 (-) 717 WP_015900794.1 quorum-sensing response regulator AgrA Regulator
  A2I63_RS04700 (A2I63_04605) agrC 1002001..1003296 (-) 1296 Protein_924 quorum-sensing sensor histidine kinase AgrC -
  A2I63_RS04705 (A2I63_04610) agrD 1003328..1003465 (-) 138 WP_015900791.1 cyclic lactone autoinducer peptide AgrD -
  A2I63_RS04710 (A2I63_04615) - 1003474..1004049 (-) 576 WP_015900790.1 accessory gene regulator AgrB -
  A2I63_RS12730 (A2I63_04620) - 1004547..1004627 (+) 81 WP_041612998.1 delta-lysin family phenol-soluble modulin -
  A2I63_RS04715 (A2I63_04625) - 1004940..1005740 (-) 801 WP_015900789.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27830.62 Da        Isoelectric Point: 4.6988

>NTDB_id=180525 A2I63_RS04695 WP_015900794.1 1001280..1001996(-) (agrA) [Staphylococcus carnosus strain TMW 2.243]
MKIIICEDDQQQRAHIEEIINNYTMIEEKPLEIALSTNDPYEVIEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSYSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSTKSHRLIAHLDNRQIEFYGSLKELSNIDERFFRCHNSFVINLNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=180525 A2I63_RS04695 WP_015900794.1 1001280..1001996(-) (agrA) [Staphylococcus carnosus strain TMW 2.243]
ATGAAAATTATTATTTGTGAAGACGACCAGCAACAACGCGCACATATCGAAGAAATTATCAATAACTATACAATGATTGA
AGAAAAGCCATTAGAAATTGCTCTCTCAACTAATGATCCATATGAAGTAATTGAATACGCTAAAAATACAAATGACATTT
GTTGTTACTTCTTAGATATTCAACTTGACGCAGATATAAATGGGATTAAACTCGGTAGTGAGTTACGTAAATTTGATACG
GTTGGGAATATTGTTTTTGTGACAAGTTATAGCGAATTGACTTACTTAACTTTTGTTTATAAAGTAGCAGCAATGGATTT
TATCTTTAAAGATGATCCTAGCGAAATGAAATCACGGATTATTGATTGCATTGAAACAGCACTTACACGTTTGCAGCTAT
TATCTAAAGAAAGCAACGTTGAAACAATCGAACTTAAAAGAGGCAGTAATTCTGTCTATGTTAATTACGATGATGTAATG
TTTTTCGAATCATCCACTAAATCTCATAGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGAAGTTTGAA
AGAACTCAGTAATATTGATGAACGCTTCTTCCGTTGTCACAACAGCTTTGTAATCAACCTCAATAATATCGAAGAAGTGA
TTTCAAAAGAACGTGAAATTCACTTTAAAAACGGCGAACATTGCTATGTCTCTGTCCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DMK5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.151

100

0.782

Multiple sequence alignment