Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A2I66_RS05015 Genome accession   NZ_CP015535
Coordinates   1051122..1051838 (-) Length   238 a.a.
NCBI ID   WP_065865277.1    Uniprot ID   -
Organism   Staphylococcus carnosus strain TMW 2.218     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1046122..1056838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2I66_RS04995 (A2I66_04905) - 1047361..1048005 (+) 645 WP_046100371.1 redox-sensing transcriptional repressor Rex -
  A2I66_RS05000 (A2I66_04910) - 1048055..1048279 (-) 225 WP_015900797.1 sulfurtransferase TusA family protein -
  A2I66_RS05005 (A2I66_04915) - 1048306..1049391 (-) 1086 WP_065865275.1 YeeE/YedE family protein -
  A2I66_RS05010 (A2I66_04920) - 1049603..1051075 (+) 1473 WP_065865276.1 GH32 C-terminal domain-containing protein -
  A2I66_RS05015 (A2I66_04925) agrA 1051122..1051838 (-) 717 WP_065865277.1 quorum-sensing response regulator AgrA Regulator
  A2I66_RS05020 (A2I66_04930) agrC 1051843..1053138 (-) 1296 WP_065865278.1 quorum-sensing sensor histidine kinase AgrC -
  A2I66_RS05025 (A2I66_04935) agrD 1053170..1053307 (-) 138 WP_015900791.1 cyclic lactone autoinducer peptide AgrD -
  A2I66_RS05030 (A2I66_04940) - 1053316..1053891 (-) 576 WP_015900790.1 accessory gene regulator AgrB -
  A2I66_RS13295 (A2I66_04945) - 1054389..1054469 (+) 81 WP_041612998.1 delta-lysin family phenol-soluble modulin -
  A2I66_RS05035 (A2I66_04950) - 1054782..1055582 (-) 801 WP_065865280.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27859.67 Da        Isoelectric Point: 4.8624

>NTDB_id=180497 A2I66_RS05015 WP_065865277.1 1051122..1051838(-) (agrA) [Staphylococcus carnosus strain TMW 2.218]
MKIIICEDDQQQRAHIEEIINNYIMIEEKPLEIALSTNDPYEVIEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSTKSHRLIAHLDNRQIEFYGSLKELSNIDERFFRCHNSFVINRNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=180497 A2I66_RS05015 WP_065865277.1 1051122..1051838(-) (agrA) [Staphylococcus carnosus strain TMW 2.218]
ATGAAAATTATTATTTGTGAAGACGACCAGCAACAACGCGCACATATCGAAGAAATTATCAATAACTATATAATGATTGA
AGAAAAGCCATTAGAAATTGCTCTCTCAACTAATGATCCATATGAAGTAATTGAATACGCTAAAAATACAAATGACATTT
GTTGTTACTTTTTAGATATTCAACTTGACGCAGATATAAATGGGATTAAACTCGGTAGTGAGTTACGTAAATTTGATACG
GTTGGGAATATTGTTTTTGTGACAAGTCATAGCGAATTGACTTACTTAACTTTTGTTTATAAAGTAGCAGCAATGGATTT
TATCTTTAAAGATGATCCTAGCGAAATGAAATCACGGATTATTGATTGCATTGAAACAGCACTTACACGTTTGCAGCTAT
TATCTAAAGAAAGCAACGTTGAAACAATCGAACTTAAAAGAGGCAGTAATTCTGTCTATGTTAATTACGATGATGTAATG
TTTTTCGAATCATCCACTAAATCTCATAGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGAAGTTTGAA
AGAACTCAGTAATATTGATGAACGCTTCTTCCGTTGTCACAACAGCTTTGTAATCAACCGCAATAATATCGAAGAAGTGA
TTTCAAAAGAACGTGAAATTCACTTTAAAAACGGCGAACATTGCTATGTCTCTGTCCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794

Multiple sequence alignment