Detailed information NTG0180475

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A2I67_RS07930
• Genome accession: NZ_CP015533
• Coordinates: 1538625..1539668 (-)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain TMW 2.216
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1533625..1544668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2I67_RS07900 (A2I67_07740)	-	1534763..1534969 (-)	207	WP_015900698.1	DUF1128 family protein	-
A2I67_RS07905 (A2I67_07745)	-	1535205..1535669 (+)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
A2I67_RS07910 (A2I67_07750)	-	1535677..1535973 (+)	297	WP_103211754.1	hypothetical protein	-
A2I67_RS07915 (A2I67_07755)	-	1536092..1537168 (+)	1077	WP_046100413.1	YihY/virulence factor BrkB family protein	-
A2I67_RS07920 (A2I67_07760)	-	1537378..1537956 (+)	579	WP_103211755.1	carbonic anhydrase	-
A2I67_RS07925 (A2I67_07765)	vraR	1538006..1538635 (-)	630	WP_046100412.1	response regulator transcription factor	Regulator
A2I67_RS07930 (A2I67_07770)	vraS	1538625..1539668 (-)	1044	WP_015900704.1	sensor histidine kinase	Regulator
A2I67_RS07935 (A2I67_07775)	liaF	1539665..1540366 (-)	702	WP_046100411.1	cell wall-active antibiotics response protein LiaF	-
A2I67_RS07940 (A2I67_07780)	-	1540382..1540777 (-)	396	WP_015900706.1	hypothetical protein	-
A2I67_RS07945 (A2I67_07785)	map	1540911..1541678 (-)	768	WP_015900707.1	type I methionyl aminopeptidase	-
A2I67_RS07950 (A2I67_07790)	-	1541930..1542916 (+)	987	WP_103211659.1	aromatic acid exporter family protein	-
A2I67_RS07955 (A2I67_07795)	-	1542966..1543691 (-)	726	WP_046100409.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=180475 A2I67_RS07930 WP_015900704.1 1538625..1539668(-) (vraS) [Staphylococcus carnosus strain TMW 2.216]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180475 A2I67_RS07930 WP_015900704.1 1538625..1539668(-) (vraS) [Staphylococcus carnosus strain TMW 2.216]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847