Detailed information NTG0180430

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A2I65_RS05415
• Genome accession: NZ_CP015532
• Coordinates: 1128684..1129727 (+)
• Length: 347 a.a.
• NCBI ID: WP_065865302.1
• Uniprot ID: -
• Organism: Staphylococcus carnosus strain TMW 2.212
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1123684..1134727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2I65_RS05390 (A2I65_05280)	-	1124661..1125386 (+)	726	WP_015900709.1	type 1 glutamine amidotransferase	-
A2I65_RS05395 (A2I65_05285)	-	1125436..1126422 (-)	987	WP_253720581.1	aromatic acid exporter family protein	-
A2I65_RS05400 (A2I65_05290)	map	1126674..1127441 (+)	768	WP_015900707.1	type I methionyl aminopeptidase	-
A2I65_RS05405 (A2I65_05295)	-	1127575..1127970 (+)	396	WP_015900706.1	hypothetical protein	-
A2I65_RS05410 (A2I65_05300)	liaF	1127986..1128687 (+)	702	WP_253720582.1	cell wall-active antibiotics response protein LiaF	-
A2I65_RS05415 (A2I65_05305)	vraS	1128684..1129727 (+)	1044	WP_065865302.1	sensor histidine kinase	Regulator
A2I65_RS05420 (A2I65_05310)	vraR	1129717..1130346 (+)	630	WP_065865303.1	response regulator transcription factor	Regulator
A2I65_RS05425 (A2I65_05315)	-	1130396..1130974 (-)	579	WP_015900702.1	carbonic anhydrase	-
A2I65_RS05430 (A2I65_05320)	-	1131184..1132260 (-)	1077	WP_065865304.1	YihY/virulence factor BrkB family protein	-
A2I65_RS05435 (A2I65_05325)	-	1132379..1132675 (-)	297	WP_015900700.1	hypothetical protein	-
A2I65_RS05440 (A2I65_05330)	-	1132683..1133147 (-)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
A2I65_RS05445 (A2I65_05335)	-	1133383..1133589 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40135.63 Da
• Isoelectric Point: 5.4382

>NTDB_id=180430 A2I65_RS05415 WP_065865302.1 1128684..1129727(+) (vraS) [Staphylococcus carnosus strain TMW 2.212]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFKVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDIDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180430 A2I65_RS05415 WP_065865302.1 1128684..1129727(+) (vraS) [Staphylococcus carnosus strain TMW 2.212]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTAAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATATAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847