Detailed information NTG0180392

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A2I62_RS05125
• Genome accession: NZ_CP015531
• Coordinates: 1082681..1083724 (+)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain TMW 2.146
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1077681..1088724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2I62_RS05100 (A2I62_05015)	-	1078658..1079383 (+)	726	WP_015900709.1	type 1 glutamine amidotransferase	-
A2I62_RS05105 (A2I62_05020)	-	1079433..1080419 (-)	987	WP_015900708.1	aromatic acid exporter family protein	-
A2I62_RS05110 (A2I62_05025)	map	1080671..1081438 (+)	768	WP_015900707.1	type I methionyl aminopeptidase	-
A2I62_RS05115 (A2I62_05030)	-	1081572..1081967 (+)	396	WP_015900706.1	hypothetical protein	-
A2I62_RS05120 (A2I62_05035)	liaF	1081983..1082684 (+)	702	WP_015900705.1	cell wall-active antibiotics response protein LiaF	-
A2I62_RS05125 (A2I62_05040)	vraS	1082681..1083724 (+)	1044	WP_015900704.1	sensor histidine kinase	Regulator
A2I62_RS05130 (A2I62_05045)	vraR	1083714..1084343 (+)	630	WP_041612989.1	response regulator transcription factor	Regulator
A2I62_RS05135 (A2I62_05050)	-	1084393..1084971 (-)	579	WP_015900702.1	carbonic anhydrase	-
A2I62_RS05140 (A2I62_05055)	-	1085181..1086257 (-)	1077	WP_015900701.1	YihY/virulence factor BrkB family protein	-
A2I62_RS05145 (A2I62_05060)	-	1086376..1086672 (-)	297	WP_015900700.1	hypothetical protein	-
A2I62_RS05150 (A2I62_05065)	-	1086680..1087144 (-)	465	WP_015900699.1	low molecular weight protein-tyrosine-phosphatase	-
A2I62_RS05155 (A2I62_05070)	-	1087380..1087586 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=180392 A2I62_RS05125 WP_015900704.1 1082681..1083724(+) (vraS) [Staphylococcus carnosus strain TMW 2.146]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180392 A2I62_RS05125 WP_015900704.1 1082681..1083724(+) (vraS) [Staphylococcus carnosus strain TMW 2.146]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847