Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   Lh8627_RS09395 Genome accession   NZ_CP015444
Coordinates   1797179..1798975 (-) Length   598 a.a.
NCBI ID   WP_003627319.1    Uniprot ID   -
Organism   Lactobacillus helveticus strain FAM8627     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1792179..1803975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Lh8627_RS09370 - 1792749..1793089 (-) 341 Protein_1805 transposase -
  Lh8627_RS09375 (Lh8627_09085) - 1793286..1794464 (+) 1179 WP_041806155.1 IS256-like element IS1201 family transposase -
  Lh8627_RS09380 (Lh8627_09090) - 1794704..1796016 (+) 1313 Protein_1807 L-lactate permease -
  Lh8627_RS09385 (Lh8627_09095) - 1796009..1796281 (+) 273 WP_020828967.1 bacteriocin immunity protein -
  Lh8627_RS11520 - 1796441..1796890 (-) 450 WP_329559911.1 Fic family protein -
  Lh8627_RS09395 (Lh8627_09105) pepF 1797179..1798975 (-) 1797 WP_003627319.1 oligoendopeptidase F Regulator
  Lh8627_RS09400 (Lh8627_09110) - 1799137..1800378 (+) 1242 WP_003627318.1 LCP family protein -
  Lh8627_RS09405 (Lh8627_09115) - 1800447..1800635 (+) 189 Protein_1812 DUF554 family protein -
  Lh8627_RS09410 (Lh8627_09120) - 1800696..1801955 (+) 1260 WP_101871892.1 RNA-guided endonuclease TnpB family protein -
  Lh8627_RS09415 (Lh8627_09125) - 1802051..1802556 (+) 506 Protein_1814 DUF554 family protein -
  Lh8627_RS09420 (Lh8627_09130) - 1802553..1803107 (-) 555 WP_020828969.1 GNAT family N-acetyltransferase -
  Lh8627_RS09425 (Lh8627_09135) - 1803241..1803618 (+) 378 WP_003630153.1 hypothetical protein -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68113.15 Da        Isoelectric Point: 4.8868

>NTDB_id=179903 Lh8627_RS09395 WP_003627319.1 1797179..1798975(-) (pepF) [Lactobacillus helveticus strain FAM8627]
MAIPTRSEVPEDLKWDLTRIFKTDQDWENAFDKAKDDVAKLSELKGSLAKSGKDLYEGLTKILAVKRDVENIYVYATMSS
DVDTSNSHYLGYVSRVQSLSNQFEATTSFINPEILSIPAEKFEQFKKDEPRLADYAHYLEMITNKRPHTLPAEEEKIIAD
AGDAMSVSENTFNVLTNSDMEYGYVQDEDGNMEQLSNGLYSLLIQSQNRDVRKGAFNTLYASYGQFQNSLASTLSGVVKK
HNYNARMHKYDSAREAALADNGVPVEVYDTLIKEVDSHLDLLHRYVALRKKILGLKDLQMWDMYVPLTGKPALSYNFEEA
KKVAKEAMKPLGEDYLKHVDYIFNNRVIDPVESKGKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
HSQPYIYGNYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNHYLDSFKGTLFRQTQFAVFEQFIHEADAKGEPLTA
DILDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGSQADRDAYLGYLKSGSSDY
PTEIMKRAGVDMTKPDYLKDAFKTFEKRLNEFESLIGK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=179903 Lh8627_RS09395 WP_003627319.1 1797179..1798975(-) (pepF) [Lactobacillus helveticus strain FAM8627]
ATGGCGATTCCAACAAGAAGCGAAGTCCCAGAAGATTTGAAGTGGGATTTAACCCGCATCTTTAAAACAGACCAAGACTG
GGAAAATGCCTTTGACAAGGCAAAAGATGACGTGGCTAAGCTAAGTGAATTAAAGGGAAGCTTGGCTAAATCAGGCAAAG
ATTTGTATGAAGGCTTGACCAAGATTTTGGCAGTTAAACGTGATGTAGAAAATATTTACGTTTATGCCACTATGTCTAGC
GATGTTGATACTTCTAACTCACATTATTTGGGCTACGTTAGCCGCGTGCAAAGCTTGTCCAATCAATTTGAAGCAACAAC
CAGTTTTATTAATCCTGAAATTTTGAGTATCCCTGCCGAAAAGTTTGAACAATTCAAAAAAGACGAGCCAAGATTAGCTG
ATTACGCCCACTATTTGGAAATGATCACTAACAAGCGTCCTCATACTTTGCCAGCAGAAGAAGAAAAAATTATCGCTGAC
GCAGGGGATGCTATGAGCGTGTCAGAGAATACCTTTAACGTTTTAACCAACTCTGACATGGAATATGGTTATGTGCAAGA
TGAAGACGGCAACATGGAGCAATTATCCAATGGCTTGTATTCATTATTGATTCAGTCCCAAAATCGTGACGTGCGTAAAG
GTGCTTTTAATACTCTCTATGCCAGCTATGGTCAATTCCAAAACTCGCTTGCCTCTACTCTCTCCGGCGTTGTGAAAAAA
CATAACTACAACGCACGCATGCACAAGTATGATTCAGCTCGTGAAGCCGCATTAGCTGATAACGGCGTACCTGTTGAAGT
TTACGACACATTAATTAAAGAAGTTGATTCACACCTTGACTTGCTTCACCGTTATGTCGCATTGCGCAAGAAAATTTTAG
GTCTTAAAGACTTACAAATGTGGGACATGTACGTGCCGCTAACTGGTAAGCCTGCTTTGTCTTACAACTTTGAAGAGGCT
AAAAAGGTAGCTAAAGAAGCCATGAAGCCACTTGGCGAAGACTACTTAAAGCATGTTGATTATATTTTTAACAACCGTGT
GATTGATCCTGTTGAATCTAAGGGCAAGGTTACTGGTGCTTACTCTGGTGGTGCTTACGATACCGATCCATATGAACTTT
TGAACTGGGAAGACAATATCGATTCACTCTATACTTTAGTTCATGAAACTGGACACTCAGTTCACTCTTGGTACACCCGC
CACAGTCAGCCTTATATCTATGGTAATTACCCAATCTTCGTGGCTGAAATTGCTTCAACCACTAATGAAAATATTTTGAC
TGAATATTTCTTGGACCATATCACTGATCCTAAGACGCGCGCATTCATCTTGAACCACTACCTTGATTCATTCAAGGGTA
CATTGTTCCGCCAAACTCAATTTGCGGTATTTGAACAATTTATCCACGAAGCAGATGCTAAGGGCGAACCATTGACTGCC
GATATTTTGGATGATGTTTATGGTCAAATTAACCAGCATTACTACGGCGACAGTGTTGAACCTGGTGGCGATATTGCGCT
TGAATGGTCACGAATTCCGCACTTCTACTACAACTTCTACGTTTATCAATATGCGACTGGATTTGCGGCTGCAACGGCTT
TGGCTAACAAGGTTGTGCATGGTAGTCAGGCTGATAGGGATGCATACCTGGGCTACCTTAAGTCAGGTTCTAGTGACTAT
CCTACTGAGATCATGAAGCGTGCCGGCGTTGACATGACTAAGCCCGATTATTTGAAAGATGCTTTCAAGACTTTTGAAAA
GAGATTGAACGAATTCGAGAGTTTGATTGGTAAGTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(203-583)

Oligopeptidase F (Peptidase_M3_N)

(113-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.178

99.331

0.508

Multiple sequence alignment