Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A6041_RS04970 Genome accession   NZ_CP015429
Coordinates   1065765..1066442 (-) Length   225 a.a.
NCBI ID   WP_172592915.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi strain GHA1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1060765..1071442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6041_RS04950 (A6041_04960) mutL 1061139..1062935 (+) 1797 WP_064082175.1 DNA mismatch repair endonuclease MutL -
  A6041_RS04955 (A6041_04965) miaA 1062999..1063940 (+) 942 WP_064082176.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  A6041_RS04960 (A6041_04970) hfq 1064003..1064308 (+) 306 WP_064082177.1 RNA chaperone Hfq -
  A6041_RS04965 (A6041_04975) hflX 1064346..1065695 (+) 1350 WP_064082178.1 ribosome rescue GTPase HflX -
  A6041_RS04970 (A6041_04980) crp 1065765..1066442 (-) 678 WP_172592915.1 cAMP-activated global transcriptional regulator CRP Regulator
  A6041_RS04975 (A6041_04985) - 1066533..1066751 (-) 219 WP_010944700.1 YheU family protein -
  A6041_RS04980 (A6041_04990) slmA 1066760..1067368 (-) 609 WP_064082180.1 nucleoid occlusion factor SlmA -
  A6041_RS04985 (A6041_04995) dut 1067472..1067927 (-) 456 WP_041603414.1 dUTP diphosphatase -
  A6041_RS04990 (A6041_05000) coaBC 1067914..1069158 (-) 1245 WP_064083358.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  A6041_RS04995 (A6041_05005) radC 1069371..1070042 (+) 672 WP_064083359.1 RadC family protein -
  A6041_RS05000 (A6041_05010) rpmB 1070203..1070439 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  A6041_RS05005 (A6041_05015) rpmG 1070451..1070621 (+) 171 WP_010944694.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25244.07 Da        Isoelectric Point: 6.2235

>NTDB_id=179532 A6041_RS04970 WP_172592915.1 1065765..1066442(-) (crp) [[Haemophilus] ducreyi strain GHA1]
MQDISISTPRLDGEVSPPPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEEANSLFYIVSGSVAVFIKDDEGKEMILSHLG
QGEFVGEISLFEENTQPRTAWVKTKDACEIAEISYEKFKQLVHVNPDILMYLAAQMACRLRQTSRQVSNLAFLDVTGRIA
QTLMNLAKMPEAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=179532 A6041_RS04970 WP_172592915.1 1065765..1066442(-) (crp) [[Haemophilus] ducreyi strain GHA1]
ATGCAAGATATTTCTATTTCTACACCTCGGCTTGATGGAGAGGTTTCCCCGCCTCCTTCGATTCATGATCCTGCGGTAGA
ATGGTTTTTAACGCACTGCCATATTCATCGCTATCCTTCAAAATATACTTTAATTCACGCAGGTGAAGAAGCAAATTCCC
TGTTTTATATTGTCAGTGGTTCTGTGGCTGTCTTTATTAAAGACGATGAAGGCAAAGAAATGATTTTATCACATCTAGGA
CAAGGAGAGTTTGTCGGCGAAATTAGTTTATTTGAAGAAAATACACAGCCAAGAACCGCTTGGGTAAAAACGAAAGATGC
TTGCGAAATTGCAGAAATTTCTTATGAAAAATTTAAACAATTAGTACATGTAAATCCTGACATTTTAATGTATCTTGCTG
CTCAAATGGCTTGTCGCTTACGTCAAACTTCGCGTCAAGTAAGTAATCTTGCTTTTTTAGATGTTACCGGTCGTATTGCG
CAAACATTGATGAATTTAGCCAAAATGCCTGAAGCAATGACGCATCCTGAAGGAATGCAAATTAAAATTACTCGCCAAGA
AATTGGGCAAATGGTGGGCTGCTCACGTGAAACTGTGGGACGCATTTTAAAAATGTTAGAAGATGAAGGTTTAATCTCAG
CCCATGGGAAGACCATAGTTGTTTATGGTACGCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-123)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

75.369

90.222

0.68
  crp Haemophilus influenzae Rd KW20

73.399

90.222

0.662
  crp Acinetobacter baumannii D1279779

49.5

88.889

0.44

Multiple sequence alignment