Detailed information NTG0178530

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: A5478_RS12845
• Genome accession: NZ_CP015342
• Coordinates: 2875184..2876446 (+)
• Length: 420 a.a.
• NCBI ID: WP_010948208.1
• Uniprot ID: Q5ZSL1
• Organism: Legionella pneumophila strain D-7632
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2870184..2881446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A5478_RS12825 (A5478_12825)	-	2870736..2871257 (+)	522	WP_062721455.1	transposase	-
A5478_RS12830 (A5478_12830)	-	2871233..2872291 (+)	1059	WP_062728974.1	IS3 family transposase	-
A5478_RS12835 (A5478_12835)	ceg32	2872393..2873898 (+)	1506	Protein_2521	Dot/Icm T4SS effector Ceg32/SidI	-
A5478_RS12840 (A5478_12840)	mesI	2873900..2874787 (+)	888	WP_010948207.1	Dot/Icm T4SS metaeffector MesI	-
A5478_RS12845 (A5478_12845)	lqsT	2875184..2876446 (+)	1263	WP_010948208.1	sensor histidine kinase	Regulator
A5478_RS12850 (A5478_12850)	-	2876494..2877189 (-)	696	WP_010948209.1	iron-containing redox enzyme family protein	-
A5478_RS12855 (A5478_12855)	sdjA	2877588..2880011 (-)	2424	WP_010948210.1	Dot/Icm T4SS effector SdjA	-
A5478_RS12860 (A5478_12860)	dupB	2880082..2881275 (-)	1194	WP_010948211.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48657.07 Da
• Isoelectric Point: 7.9744

>NTDB_id=178530 A5478_RS12845 WP_010948208.1 2875184..2876446(+) (lqsT) [Legionella pneumophila strain D-7632]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALILLISGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFSIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKEGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=178530 A5478_RS12845 WP_010948208.1 2875184..2876446(+) (lqsT) [Legionella pneumophila strain D-7632]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTCTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTGCCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCGACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTTTCCAGTGTATTGGGGGCTCTTATAT
TACTTATATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGTGCCTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCCGAATTACAGGAATTGATTGTCGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGCATAGAAATGAGTAATCAATTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTTCGATTTATTCCATCAAAAAATTGCTCAAGGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGTCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGAAGGAACTGGTTTAGGCTTGGCCTATTGTAAACTTCTGATGCAAGCAGCAGGCGGTGATATT
TCCTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5ZSL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	100	100	1