Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   V471_RS05060 Genome accession   NZ_CP015283
Coordinates   973413..975218 (+) Length   601 a.a.
NCBI ID   WP_084871169.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 970259..983201 973413..975218 within 0


Gene organization within MGE regions


Location: 970259..983201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS05050 (V471_04980) - 970259..971278 (-) 1020 WP_171021848.1 IS30-like element IS1139 family transposase -
  V471_RS05055 (V471_04985) - 972443..973402 (+) 960 WP_084871168.1 competence protein CoiA -
  V471_RS05060 (V471_04990) pepF 973413..975218 (+) 1806 WP_084871169.1 oligoendopeptidase F Regulator
  V471_RS05065 (V471_04995) - 975430..976650 (+) 1221 WP_045769259.1 OFA family MFS transporter -
  V471_RS05070 (V471_05000) - 976722..977429 (+) 708 WP_014633986.1 O-methyltransferase -
  V471_RS05075 (V471_05005) - 977491..978633 (+) 1143 WP_002886735.1 peptidyl-prolyl cis-trans isomerase -
  V471_RS05080 (V471_05010) - 978972..979457 (+) 486 WP_013990151.1 LURP-one-related/scramblase family protein -
  V471_RS05085 (V471_05015) alaS 979482..982100 (+) 2619 WP_049553646.1 alanine--tRNA ligase -
  V471_RS05090 (V471_05020) - 982278..983201 (+) 924 WP_084871170.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69066.11 Da        Isoelectric Point: 4.5371

>NTDB_id=178304 V471_RS05060 WP_084871169.1 973413..975218(+) (pepF) [Streptococcus salivarius strain ATCC 25975]
MSDNRAHLEEKYTWDLTTIFATDADWETEYESTVQDLKKASAYAGHLLDSAKNLLEATELYMSLMRRLEKIYVYASMKND
QDTTVGLYQEYQAKASNLYSQLSEAFAYFEPEFMALDDKKLAEFKEQEPGLGLYDHYFERLLANKDHVLSQEAEELLAAA
GDIFNGPTDTFNVLDNADILFPWVSDGQGDVVELTHGNFITLMESKDRDIRKGTYEAMYGTYEQFQHTYAQTLQGVVKVH
NYQAKVRHYNSARHAALAANFIPESVYDSLLESVNKYLPLLHRYLDLRKKVLGLDELKMYDVYTPLSETETALTYEESLK
KAEEVLAIFGEEYSKGVHAAFTERWIDVHPNKGKRSGAYSGGAYDTNAFMLLNWQDTLDNLFTLVHETGHSLHSTFTRQT
QPYVYGDYPIFLAEIASTTNENILTETLLKEVKDDKARFAILNHYLDGFKGTVFRQTQFAEFEHAIHEADASGQILTADF
MNKLYADLNEKYYNLKAEDNYEIQFEWERIPHFYMNYYVYQYATGFAAASYLAEKIVHGTEEDKEAYLTYLKAGSSDYPL
EVIKKAGVDMTNTDYLDAAFKVFEDRLVELEALVEKGVHLS

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=178304 V471_RS05060 WP_084871169.1 973413..975218(+) (pepF) [Streptococcus salivarius strain ATCC 25975]
ATGTCAGACAATCGTGCTCATTTAGAAGAGAAATACACATGGGATTTGACGACCATTTTTGCGACAGATGCAGATTGGGA
GACTGAATATGAAAGCACTGTTCAGGATTTGAAGAAGGCTAGTGCTTATGCAGGTCATCTCTTAGATTCTGCTAAGAACT
TGCTTGAGGCAACTGAACTTTATATGAGTCTTATGCGTCGCTTGGAGAAAATCTATGTCTATGCGTCAATGAAAAATGAC
CAAGACACAACAGTAGGGCTTTACCAAGAGTACCAAGCTAAGGCCTCAAACCTTTACTCACAGTTGAGTGAAGCTTTTGC
ATACTTTGAGCCTGAATTTATGGCCTTGGATGATAAGAAATTAGCTGAATTTAAAGAACAAGAGCCAGGTCTTGGGCTTT
ATGACCACTATTTTGAACGCCTTTTGGCAAACAAGGACCATGTTCTTTCTCAAGAAGCTGAAGAGCTCTTGGCAGCAGCC
GGTGATATCTTCAACGGTCCAACGGATACCTTCAATGTCTTGGATAATGCTGATATCCTCTTCCCATGGGTATCAGATGG
TCAAGGGGATGTGGTTGAGTTGACACATGGTAACTTTATCACTCTTATGGAATCTAAGGACCGTGACATTCGTAAGGGAA
CCTATGAAGCGATGTATGGGACTTACGAACAGTTCCAACATACTTATGCACAAACACTCCAAGGTGTTGTTAAGGTTCAC
AATTACCAAGCCAAAGTTCGTCACTATAATTCGGCACGTCATGCAGCACTTGCGGCTAACTTTATTCCAGAGAGTGTTTA
TGATTCACTCTTGGAATCAGTGAACAAGTATTTGCCACTTTTGCACCGTTACCTTGATTTGCGTAAGAAGGTCTTGGGAC
TTGACGAGCTTAAGATGTATGACGTCTATACACCACTTTCTGAGACTGAAACTGCTCTTACTTATGAAGAATCTCTAAAG
AAAGCAGAAGAAGTCTTGGCAATCTTTGGTGAAGAGTATAGTAAAGGGGTTCATGCAGCCTTTACGGAACGTTGGATTGA
CGTTCACCCTAACAAAGGAAAACGCTCAGGTGCCTACTCAGGTGGTGCCTATGATACCAATGCTTTCATGCTTTTGAACT
GGCAAGACACTTTGGACAATCTCTTTACCTTGGTTCACGAGACTGGCCACAGTTTGCATTCAACTTTCACACGTCAGACT
CAACCATATGTTTACGGAGATTACCCAATCTTCTTGGCGGAAATTGCGTCTACAACCAATGAAAATATCTTGACAGAAAC
GCTTCTTAAAGAGGTTAAAGATGACAAGGCACGTTTTGCTATTCTTAACCACTATTTGGATGGTTTCAAGGGAACTGTCT
TCCGTCAAACACAATTTGCCGAGTTTGAGCATGCTATCCATGAGGCAGATGCATCTGGTCAAATCTTGACAGCGGACTTC
ATGAATAAGCTTTACGCAGACCTCAATGAGAAATACTATAACCTTAAAGCTGAGGATAACTACGAAATTCAGTTTGAGTG
GGAACGTATTCCGCATTTCTACATGAATTACTATGTCTACCAATACGCTACAGGATTTGCTGCGGCAAGCTACTTGGCTG
AAAAAATTGTTCACGGTACTGAAGAAGATAAAGAAGCTTACCTTACTTACCTTAAGGCGGGAAGCTCAGACTATCCTTTG
GAAGTCATCAAGAAAGCTGGTGTTGATATGACCAATACCGACTACTTAGATGCTGCCTTCAAAGTTTTTGAAGACCGTCT
TGTTGAATTGGAAGCTTTGGTTGAAAAAGGTGTTCACCTTTCTTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

99.168

100

0.992

Multiple sequence alignment