Detailed information NTG0178284

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V471_RS03315
• Genome accession: NZ_CP015283
• Coordinates: 627070..629520 (+)
• Length: 816 a.a.
• NCBI ID: WP_070849930.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 622070..634520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS03290 (V471_03260)	ahpC	622968..623528 (-)	561	WP_084871103.1	alkyl hydroperoxide reductase subunit C	-
V471_RS03295 (V471_03265)	rpsB	623801..624568 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
V471_RS03300 (V471_03270)	tsf	624679..625719 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
V471_RS03305 (V471_03275)	-	625826..626296 (-)	471	WP_002886344.1	COG2426 family protein	-
V471_RS03310 (V471_03280)	-	626614..627069 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
V471_RS03315 (V471_03285)	clpC	627070..629520 (+)	2451	WP_070849930.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V471_RS03320 (V471_03290)	pbp3	629649..630905 (-)	1257	WP_045768740.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
V471_RS03325 (V471_03295)	pbp3	631050..632297 (-)	1248	WP_002886348.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90326.65 Da
• Isoelectric Point: 5.7203

>NTDB_id=178284 V471_RS03315 WP_070849930.1 627070..629520(+) (clpC) [Streptococcus salivarius strain ATCC 25975]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEVMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPEPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTIGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMMKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=178284 V471_RS03315 WP_070849930.1 627070..629520(+) (clpC) [Streptococcus salivarius strain ATCC 25975]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACAGCCGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCCGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGTTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAGGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTTTTTATTGACGAATTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGCACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTACCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAGAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCATAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGCCTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTCGATTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTATTGGATTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGATGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGCACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (378-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	94.975	100	0.95
clpC	Streptococcus thermophilus LMD-9	94.853	100	0.949
clpC	Streptococcus mutans UA159	72.672	100	0.727
clpC	Streptococcus pneumoniae TIGR4	67.157	100	0.672
clpC	Streptococcus pneumoniae Rx1	67.034	100	0.67
clpC	Streptococcus pneumoniae D39	67.034	100	0.67
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.388	100	0.478
clpE	Streptococcus mutans UA159	47.764	76.716	0.366