Detailed information NTG0178265

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: V471_RS00910
• Genome accession: NZ_CP015283
• Coordinates: 181973..183049 (-)
• Length: 358 a.a.
• NCBI ID: WP_002884703.1
• Uniprot ID: A0A1W5ZBL0
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 176973..188049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS00885 (V471_00890)	-	177120..177902 (+)	783	WP_014632681.1	ABC transporter ATP-binding protein	-
V471_RS00890 (V471_00895)	-	178086..180152 (-)	2067	WP_049529032.1	cation:proton antiporter	-
V471_RS00895 (V471_00900)	-	180161..180403 (-)	243	WP_002891697.1	hypothetical protein	-
V471_RS00900 (V471_00905)	-	180400..180948 (-)	549	WP_049529030.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
V471_RS00905 (V471_00910)	-	180945..181889 (-)	945	WP_014632678.1	TIGR01212 family radical SAM protein	-
V471_RS00910 (V471_00915)	sepM	181973..183049 (-)	1077	WP_002884703.1	SepM family pheromone-processing serine protease	Regulator
V471_RS00915 (V471_00920)	coaD	183027..183524 (-)	498	WP_014632676.1	pantetheine-phosphate adenylyltransferase	-
V471_RS00920 (V471_00925)	rsmD	183557..184105 (-)	549	WP_231910681.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
V471_RS00925 (V471_00930)	trxB	184245..185165 (-)	921	WP_014632674.1	thioredoxin-disulfide reductase	-
V471_RS00930 (V471_00935)	-	185231..185455 (-)	225	WP_002884393.1	DUF4059 family protein	-
V471_RS00935 (V471_00940)	-	185667..186410 (-)	744	WP_014632672.1	amino acid ABC transporter ATP-binding protein	-
V471_RS00940 (V471_00945)	-	186410..187156 (-)	747	WP_096832659.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 38988.67 Da
• Isoelectric Point: 9.2472

>NTDB_id=178265 V471_RS00910 WP_002884703.1 181973..183049(-) (sepM) [Streptococcus salivarius strain ATCC 25975]
MANKNESKSLLGKIWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSADLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKADPD
AKTNYQEAKEAAKKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=178265 V471_RS00910 WP_002884703.1 181973..183049(-) (sepM) [Streptococcus salivarius strain ATCC 25975]
GTGGCAAACAAGAACGAATCTAAATCACTATTAGGGAAAATTTGGCGGATTAAGTGGTGGTTGTTAAGTATTTTTACGGT
ACTTTTCCTCCTATTTGCCCTCTTTTTCCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACTAAGG
AAGTCTTGACTGTAGACAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCAGTGGCCCAAACCAAGGCGACT
TTAGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTGAAGAGGCAACTGGGAATTACTCTGA
TGAAGATTTCATGCGTATCAACCAATTTTACATGGAGACTTCCCAAAACCAAGCGATTTATCAGGGCTTGACTCTGGCCG
GTAAGGAGGCTAGCTTGGAGTATATGGGTGTCTATGTGCTTCAGGTGGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCGGATACGGTGACAGCTGTCAATGGCAAGACCTTTGATAATTCTGCTGACTTGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCCACTGGTAAGATTATCAAGATTGCCA
ATGGTAAAAATGGTATTGGTATCGGTTTGACAGATCATACCGAGGTTAAGAGTCCTGAAAATGTGAAGTTTAAACTTGAT
GGCGTTGGCGGACCAAGTGCGGGTCTTATGTTTACCCTAGCTATTTACGATCAGGTATCTGGTCAAGACCTCAAGGCTGG
CCGTAAGATTGCTGGAACAGGAACCATTGAAAAGGATGGTTCGGTCGGTGATATCGGTGGTGCCTACCTCAAGGTGAAAT
CAGCGGCTGATAGTGGTGCAGACATTTTCTTCGTGCCAAATAATCCAGTAACCAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAAACCAACTATCAAGAGGCCAAGGAAGCTGCCAAGAAACTGGGAACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A1W5ZBL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	65.396	95.251	0.623