Detailed information NTG0178226

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NX99_RS06355
• Genome accession: NZ_CP015282
• Coordinates: 1430675..1433125 (-)
• Length: 816 a.a.
• NCBI ID: WP_084915124.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 27945
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1425675..1438125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX99_RS06345 (NX99_06215)	pbp3	1427899..1429146 (+)	1248	WP_022496762.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
NX99_RS06350 (NX99_06220)	pbp3	1429291..1430547 (+)	1257	WP_084915122.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
NX99_RS06355 (NX99_06225)	clpC	1430675..1433125 (-)	2451	WP_084915124.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NX99_RS06360 (NX99_06230)	-	1433126..1433581 (-)	456	WP_014633783.1	CtsR family transcriptional regulator	-
NX99_RS06365 (NX99_06235)	-	1433899..1434369 (+)	471	WP_004182164.1	COG2426 family protein	-
NX99_RS06370 (NX99_06240)	tsf	1434476..1435516 (-)	1041	WP_002886343.1	translation elongation factor Ts	-
NX99_RS06375 (NX99_06245)	rpsB	1435627..1436394 (-)	768	WP_002886342.1	30S ribosomal protein S2	-
NX99_RS06380 (NX99_06250)	ahpC	1436667..1437227 (+)	561	WP_022496765.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90249.60 Da
• Isoelectric Point: 5.9166

>NTDB_id=178226 NX99_RS06355 WP_084915124.1 1430675..1433125(-) (clpC) [Streptococcus salivarius strain ATCC 27945]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEAMLQEAEGIAGVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKAIQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDRLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=178226 NX99_RS06355 WP_084915124.1 1430675..1433125(-) (clpC) [Streptococcus salivarius strain ATCC 27945]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACAGCCGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCGCATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTGGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTCCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCCCAATCTTCTACTGGGGAACTGTCAGATTATACCAAAGACTTAACGGCAGTAGCCGAATCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTGGCACAACGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCGAATATTTTGAAACCTGCTCTAGCACGTGGAACCCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGTCGTTTTGCTAAAATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCGGTCAAGGCGGCCCACCGTTATTTGACGAGTAAAAACTTACCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTATCCAAAAAGCAAAATTACCAAAACCTGCCTTA
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGATGAAGCAGTTTCAGCCATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTTGACTTTTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTGTTGGTTTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATTATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTTGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCCCTTAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCCCGCC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAGGTTATCTGAGCTCTTACTAGGTGGCCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA lid domain (AAA_lid_9) (377-455)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (109-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.221	100	0.952
clpC	Streptococcus thermophilus LMD-9	95.098	100	0.951
clpC	Streptococcus mutans UA159	72.917	100	0.729
clpC	Streptococcus pneumoniae TIGR4	67.279	100	0.673
clpC	Streptococcus pneumoniae Rx1	67.279	100	0.673
clpC	Streptococcus pneumoniae D39	67.279	100	0.673
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.542	100	0.515
clpC	Bacillus subtilis subsp. subtilis str. 168	46.78	100	0.472
clpE	Streptococcus mutans UA159	48.243	76.716	0.37