Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   A4265_RS09395 Genome accession   NZ_CP015238
Coordinates   49362..49457 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NS53     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 44362..54457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4265_RS00190 (A4265_00125) - 45184..46296 (+) 1113 WP_063631699.1 DUF262 domain-containing protein -
  A4265_RS00195 (A4265_00130) - 46300..46908 (+) 609 WP_032464127.1 hypothetical protein -
  A4265_RS00200 (A4265_00135) purB 46918..48210 (+) 1293 WP_032464128.1 adenylosuccinate lyase -
  A4265_RS00205 (A4265_00140) rgg4 48341..49278 (+) 938 Protein_34 transcriptional regulator Rgg4/ComR -
  A4265_RS09395 comS 49362..49457 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  A4265_RS00210 (A4265_00145) ruvB 49504..50502 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  A4265_RS00215 (A4265_00150) - 50640..51077 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  A4265_RS00220 (A4265_00155) - 51100..51501 (+) 402 WP_012560369.1 MORN repeat-containing protein -
  A4265_RS00225 (A4265_00160) - 51498..53273 (+) 1776 WP_063631700.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=177926 A4265_RS09395 WP_198462994.1 49362..49457(+) (comS) [Streptococcus pyogenes strain NS53]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=177926 A4265_RS09395 WP_198462994.1 49362..49457(+) (comS) [Streptococcus pyogenes strain NS53]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment