Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A4A60_RS06615 Genome accession   NZ_CP015222
Coordinates   1295099..1295755 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain HRBS-10TDI13     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1290099..1300755
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4A60_RS06590 (A4A60_06600) oppF 1290563..1291480 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  A4A60_RS06595 (A4A60_06605) yjbB 1291588..1292805 (+) 1218 WP_072592593.1 MFS transporter -
  A4A60_RS06600 (A4A60_06610) yjbC 1292969..1293547 (+) 579 Protein_1241 GNAT family N-acetyltransferase -
  A4A60_RS06605 (A4A60_06615) spx 1293728..1294123 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  A4A60_RS06610 (A4A60_06620) yjbE 1294166..1294822 (-) 657 WP_014479447.1 TerC family protein -
  A4A60_RS22930 - 1294992..1295132 (+) 141 WP_119122854.1 hypothetical protein -
  A4A60_RS06615 (A4A60_06625) mecA 1295099..1295755 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  A4A60_RS22935 - 1295750..1295872 (-) 123 WP_003245684.1 hypothetical protein -
  A4A60_RS06620 (A4A60_06630) coiA 1295946..1297067 (+) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  A4A60_RS06625 (A4A60_06635) pepF 1297297..1299126 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  A4A60_RS06630 (A4A60_06640) - 1299164..1299331 (-) 168 WP_003244944.1 hypothetical protein -
  A4A60_RS06640 (A4A60_06650) spxH 1299646..1300545 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=177640 A4A60_RS06615 WP_014479448.1 1295099..1295755(+) (mecA) [Bacillus subtilis strain HRBS-10TDI13]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=177640 A4A60_RS06615 WP_014479448.1 1295099..1295755(+) (mecA) [Bacillus subtilis strain HRBS-10TDI13]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment