Detailed information NTG0177249

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A5J11_RS03070
• Genome accession: NZ_CP015173
• Coordinates: 584603..585490 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain RIVM6519
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 579603..590490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A5J11_RS03035 (A5J11_03035)	-	579621..579713 (+)	93	WP_010956583.1	hypothetical protein	-
A5J11_RS03040 (A5J11_03040)	-	579821..580318 (-)	498	WP_001065268.1	glutathione peroxidase	-
A5J11_RS03045 (A5J11_03045)	-	580328..580588 (-)	261	WP_001791974.1	hypothetical protein	-
A5J11_RS03050 (A5J11_03050)	-	580970..581083 (-)	114	Protein_583	hypothetical protein	-
A5J11_RS03060 (A5J11_03060)	-	581743..583743 (-)	2001	WP_000776751.1	ABC transporter permease	-
A5J11_RS03065 (A5J11_03065)	-	583740..584495 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A5J11_RS03070 (A5J11_03070)	braS	584603..585490 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A5J11_RS03075 (A5J11_03075)	braR	585501..586166 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A5J11_RS03080 (A5J11_03080)	-	586192..586392 (-)	201	WP_000604730.1	hypothetical protein	-
A5J11_RS03090 (A5J11_03090)	-	586590..588014 (+)	1425	WP_063124937.1	alkaline phosphatase	-
A5J11_RS15055	-	588074..588175 (-)	102	WP_000731976.1	SE2200 family small protein	-
A5J11_RS03095 (A5J11_03095)	-	588297..588752 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A5J11_RS03100 (A5J11_03100)	-	588997..589758 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=177249 A5J11_RS03070 WP_000143425.1 584603..585490(-) (braS) [Staphylococcus aureus strain RIVM6519]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=177249 A5J11_RS03070 WP_000143425.1 584603..585490(-) (braS) [Staphylococcus aureus strain RIVM6519]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1