Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   BUM80_RS05535 Genome accession   NZ_CP018838
Coordinates   1026541..1027218 (-) Length   225 a.a.
NCBI ID   WP_000548993.1    Uniprot ID   A0ABM7UVF5
Organism   Streptococcus pneumoniae strain 11A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1021541..1032218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM80_RS05495 (BUM80_05670) - 1021702..1022331 (-) 630 WP_000762088.1 NAD(P)-dependent oxidoreductase -
  BUM80_RS12130 - 1022570..1022944 (+) 375 Protein_1044 hypothetical protein -
  BUM80_RS05515 (BUM80_05685) - 1023201..1023341 (+) 141 WP_000422775.1 MazG-like protein -
  BUM80_RS05520 (BUM80_05690) - 1023348..1023524 (+) 177 WP_000166032.1 hypothetical protein -
  BUM80_RS05525 (BUM80_05695) thrS 1023582..1025525 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  BUM80_RS05530 (BUM80_05700) - 1025574..1026548 (-) 975 WP_100910902.1 HAMP domain-containing histidine kinase -
  BUM80_RS05535 (BUM80_05705) braR 1026541..1027218 (-) 678 WP_000548993.1 response regulator transcription factor Regulator
  BUM80_RS05540 (BUM80_05710) - 1027374..1028447 (+) 1074 WP_001273835.1 DUF2974 domain-containing protein -
  BUM80_RS05545 (BUM80_05715) - 1028589..1028840 (-) 252 WP_001810245.1 hypothetical protein -
  BUM80_RS05550 (BUM80_05720) - 1028908..1029345 (-) 438 WP_001166791.1 Rrf2 family transcriptional regulator -
  BUM80_RS05555 (BUM80_05725) - 1029421..1030263 (-) 843 WP_000160934.1 metallophosphoesterase -
  BUM80_RS05560 (BUM80_05730) - 1030375..1031025 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  BUM80_RS05570 (BUM80_05740) dtd 1031642..1032085 (-) 444 WP_000691400.1 D-aminoacyl-tRNA deacylase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25922.08 Da        Isoelectric Point: 5.1362

>NTDB_id=176343 BUM80_RS05535 WP_000548993.1 1026541..1027218(-) (braR) [Streptococcus pneumoniae strain 11A]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDVHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=176343 BUM80_RS05535 WP_000548993.1 1026541..1027218(-) (braR) [Streptococcus pneumoniae strain 11A]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
CCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGAGACGAAAGTTTACTGGAATACGCTGGTG
TTATCCTCAATACCAAATCCATGGATGTACATTATCAAGGGCAAGTCTTAAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTTTTGTTTGAGCATGCAGGCAACATCGTAGCGCGTGATGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCAGTTAATGTGGCTCGTTTGCGTAAAAAGTTGGAAGAGCAGGGCTTGGTAGGATTTATCGAGA
CCAAGAAAGGGATAGGGTACGGACTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.541

96.889

0.48

Multiple sequence alignment