Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   A3217_RS06150 Genome accession   NZ_CP014991
Coordinates   1266496..1268400 (+) Length   634 a.a.
NCBI ID   WP_066388943.1    Uniprot ID   -
Organism   Helicobacter himalayensis strain YS1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1261496..1273400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A3217_RS06125 - 1261957..1263174 (-) 1218 WP_066388936.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  A3217_RS06130 - 1263184..1263591 (-) 408 WP_066388937.1 4Fe-4S dicluster-binding protein -
  A3217_RS06135 - 1263634..1264194 (-) 561 WP_066388938.1 pyruvate flavodoxin oxidoreductase subunit gamma -
  A3217_RS06140 - 1264406..1265119 (+) 714 WP_066388940.1 hypothetical protein -
  A3217_RS06145 - 1265147..1266499 (+) 1353 WP_066388941.1 CCA tRNA nucleotidyltransferase -
  A3217_RS06150 uvrC 1266496..1268400 (+) 1905 WP_066388943.1 excinuclease ABC subunit UvrC Machinery gene
  A3217_RS06155 - 1268499..1271387 (-) 2889 WP_066388944.1 TonB-dependent receptor plug domain-containing protein -
  A3217_RS06160 - 1271659..1272735 (-) 1077 WP_066388948.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase -

Sequence

Protein


Download         Length: 634 a.a.        Molecular weight: 72292.64 Da        Isoelectric Point: 10.0497

>NTDB_id=175821 A3217_RS06150 WP_066388943.1 1266496..1268400(+) (uvrC) [Helicobacter himalayensis strain YS1]
MNLSLSTLPESAGVYQYFDKDDKLLYVGKAKNLKKRIKSYFAKNANLSQRIAIMVSQIARIHTLVTPNEQDALILENSLI
KSLKPKYNILLRDDKTYPYIFIDKNKDFLTLEITRSVINKKNILYFGPFSFGARDLVDGILETTPLVQKKSCLQGKKACL
FYQIKRCLAPCEGKISKQEYEKILNSALELLENKKKLIKLLESKMQIFAQNYAYEEAARLRDRISKISQMQKHSVIDLAQ
SCDMDIFVFATRAQKTQIQTKAQKGAMQKGVLMKLFVRNGRISSSDFVLLHISALDMVDSDSLKSAQSPRTQSTESSTTN
HNLCSLYTQVLLNHYKAHTPLLPDSILLPANITLEGKDELERILQERLGKKIEILQPKKGKKLELINLARKNALELLHLH
TNEENIQESRLLEQIATLFGLDEIPYRIEVFDTSHHSGAQCVGAMVVYENGEFRKDSYRQYNLSGSDEYAQMSELLTRRA
LDFENNPAPNLWLLDGGKAQLKLARQILESSGTQVDTLAISKHKLNGRAHRAKGSAQDILHAVQKSTQEPKEFKLSPNDK
SLQFLQKLRDEAHRFAITFHRAQKNKNLTKLKTLTQMRALTPAQVDKLLRIYGEVRVIEKLSNEEITNALRKRG

Nucleotide


Download         Length: 1905 bp        

>NTDB_id=175821 A3217_RS06150 WP_066388943.1 1266496..1268400(+) (uvrC) [Helicobacter himalayensis strain YS1]
ATGAATCTCTCCCTCTCCACCCTGCCAGAAAGTGCTGGTGTGTATCAGTATTTTGACAAAGATGACAAACTACTCTATGT
TGGCAAGGCAAAAAATCTCAAAAAGCGCATTAAAAGCTACTTTGCCAAAAATGCCAACCTAAGCCAGCGCATAGCCATTA
TGGTATCTCAAATCGCACGTATCCACACGCTTGTAACGCCAAATGAACAAGATGCGTTGATTTTAGAAAACTCGCTTATT
AAAAGCCTCAAGCCAAAATACAATATTTTGCTGCGCGATGACAAGACTTATCCTTATATTTTTATTGATAAAAATAAAGA
CTTCCTAACGCTTGAAATAACGCGCAGTGTGATAAACAAAAAGAATATTTTGTATTTTGGTCCTTTTAGTTTTGGTGCGC
GCGACTTGGTTGATGGGATTTTAGAAACCACACCTTTAGTGCAGAAAAAATCCTGTCTTCAAGGTAAAAAAGCCTGTCTT
TTTTATCAAATCAAACGTTGTCTTGCGCCGTGTGAAGGCAAAATAAGCAAGCAAGAATATGAAAAGATTCTCAATTCCGC
ACTAGAACTTTTAGAAAACAAAAAAAAGCTTATCAAACTTTTAGAATCTAAAATGCAAATTTTTGCGCAAAACTACGCTT
ACGAAGAGGCGGCGCGCTTGAGAGATAGAATCTCCAAAATCTCACAAATGCAAAAGCACTCTGTGATTGACTTGGCGCAG
TCTTGCGATATGGATATTTTTGTCTTTGCTACGCGCGCGCAAAAAACACAAATCCAAACAAAAGCGCAAAAAGGTGCGAT
GCAAAAAGGCGTGTTGATGAAGCTATTTGTGCGAAATGGGCGCATAAGCTCGAGTGATTTTGTCTTGCTTCATATTAGCG
CACTTGATATGGTGGATTCAGATTCTCTAAAATCCGCGCAATCCCCCCGCACGCAATCCACAGAATCTAGCACGACAAAT
CACAATCTTTGCTCGCTTTACACACAAGTCCTACTTAATCACTACAAGGCGCACACACCACTTTTGCCAGATTCTATCCT
TTTGCCCGCAAATATCACACTTGAGGGCAAAGATGAGCTAGAGCGCATTTTACAAGAGCGTTTGGGTAAAAAAATCGAGA
TTTTACAACCCAAAAAAGGCAAAAAATTAGAGCTTATCAACCTTGCGCGCAAAAATGCCCTAGAGCTTTTGCATCTGCAT
ACAAATGAGGAAAATATCCAAGAATCTAGACTTTTGGAACAAATCGCTACGCTTTTTGGGCTTGATGAGATTCCTTACAG
AATCGAGGTTTTTGACACTTCGCACCACAGCGGGGCGCAGTGCGTGGGTGCTATGGTGGTGTATGAAAATGGAGAGTTTA
GAAAGGATTCTTATCGGCAGTATAATTTAAGTGGAAGTGATGAATACGCGCAAATGAGCGAGCTTCTAACGCGCCGTGCG
CTAGATTTTGAAAATAATCCCGCGCCAAATCTCTGGCTTCTTGATGGGGGCAAGGCGCAACTCAAACTCGCGCGCCAAAT
TCTAGAATCTAGTGGCACACAAGTCGATACACTCGCTATCTCAAAGCATAAGCTCAATGGACGCGCACACCGCGCAAAAG
GAAGCGCACAAGATATTTTGCACGCAGTGCAAAAAAGCACGCAAGAGCCAAAAGAATTCAAGCTTTCCCCAAATGATAAA
AGCTTGCAGTTTTTGCAAAAACTACGCGATGAGGCACACCGCTTTGCTATTACTTTCCATAGGGCGCAGAAAAATAAAAA
TCTCACAAAGCTCAAAACGCTCACCCAAATGCGCGCACTTACACCCGCCCAAGTGGATAAATTACTTAGAATCTATGGCG
AAGTGCGCGTGATTGAAAAACTCTCAAATGAGGAAATCACAAACGCACTAAGAAAAAGAGGTTGA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(417-577)

GIY-YIG catalytic domain (GIY-YIG)

(13-88)

UvrB/uvrC motif (UVR)

(195-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.922

100

0.503

Multiple sequence alignment