Detailed information NTG0174706

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A3L20_RS06415
• Genome accession: NZ_CP014847
• Coordinates: 1250169..1252769 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365378.1
• Uniprot ID: A0A9W3P241
• Organism: Bacillus thuringiensis strain HD12
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1245169..1257769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A3L20_RS06385 (A3L20_06385)	prsA	1245932..1246789 (-)	858	WP_001214205.1	peptidylprolyl isomerase PrsA	-
A3L20_RS33115	-	1246919..1247050 (-)	132	WP_001120851.1	DUF3941 domain-containing protein	-
A3L20_RS06390 (A3L20_06390)	-	1247151..1248008 (+)	858	WP_000364431.1	YitT family protein	-
A3L20_RS06395 (A3L20_06395)	-	1248034..1248231 (-)	198	WP_000527408.1	DUF3813 domain-containing protein	-
A3L20_RS06400 (A3L20_06400)	-	1248232..1248372 (-)	141	WP_000516816.1	hypothetical protein	-
A3L20_RS06405 (A3L20_06405)	-	1248478..1249287 (-)	810	WP_001041241.1	Cof-type HAD-IIB family hydrolase	-
A3L20_RS06410 (A3L20_06410)	-	1249778..1249957 (+)	180	WP_000531422.1	YjzC family protein	-
A3L20_RS06415 (A3L20_06415)	clpC	1250169..1252769 (+)	2601	WP_000365378.1	ATP-dependent chaperone ClpB	Regulator
A3L20_RS06420 (A3L20_06420)	-	1252808..1252990 (-)	183	WP_001211116.1	YjzD family protein	-
A3L20_RS06425 (A3L20_06425)	-	1253147..1253881 (+)	735	WP_000028706.1	hypothetical protein	-
A3L20_RS06430 (A3L20_06430)	-	1253911..1254783 (+)	873	WP_000486171.1	NAD-dependent epimerase/dehydratase family protein	-
A3L20_RS06435 (A3L20_06435)	comZ	1254838..1255014 (+)	177	WP_001003335.1	ComZ family protein	Regulator
A3L20_RS06440 (A3L20_06440)	fabH	1255246..1256178 (+)	933	WP_001100533.1	beta-ketoacyl-ACP synthase III	-
A3L20_RS06445 (A3L20_06445)	fabF	1256210..1257448 (+)	1239	WP_000412645.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97512.45 Da
• Isoelectric Point: 5.1561

>NTDB_id=174706 A3L20_RS06415 WP_000365378.1 1250169..1252769(+) (clpC) [Bacillus thuringiensis strain HD12]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAESLIKKKPSVTGSGAE
VGKLYITGALQQLFVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRDLVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=174706 A3L20_RS06415 WP_000365378.1 1250169..1252769(+) (clpC) [Bacillus thuringiensis strain HD12]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGTTAGCAGTGCGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAGCAAGGCGCCGAAAGTTTAATTAAGAAAAAGCCTTCTGTAACGGGAAGCGGTGCAGAA
GTAGGCAAATTATATATAACAGGTGCTCTGCAACAACTATTTGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA
CTACATTTCAGTGGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATCAATCAATTATTTACAAGATTTCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGCCGTGATTTAGTGGCAGAAGTGAGAGCAGGGAAAATTGATCCTGTTATTGGCCGGGA
TAGTGAAATTCGACGTGTCATTCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGTTAGCGCAGCGTATTGTGAAAAAAGATGTACCTGAAGGGCTAAAAGATAGAACGATC
TTCGCGTTAGATATGAGTGCGCTCGTAGCTGGTGCGAAATTCCGTGGTGAGTTCGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGGCGTATTTTATTATTTATTGATGAACTTCATACAATCGTTGGCGCCGGTAAAACAGAAG
GTGCGATGGATGCAGGGAATATGTTAAAACCGATGCTTGCTCGCGGTGAACTACACTGTATTGGGGCGACGACATTAGAT
GAATATCGTAAATATATTGAGAAAGACCCGGCGTTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCATGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCGGACCGTTTCTTACCAGATAAAGCAATTGATCTTGTCGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCGACAGAATTAGATGAAGTAACGCGTCGTATTATGCAGTTAGAAAT
TGAGGAAGCAGCTCTTGGAAAAGAAACAGATCGTGGTAGCCAAGAACGTCTTAAAACGTTGCAACGTGAACTATCAGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCGAAATGGGAGAAAGAAAAAGAAGACATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAACGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCCGAACTTCGTCACGG
GAAAATTCCAGCAATTGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAAATTGCAGATATTGTTTCACGCTGGACTGGTATTCCTGTTGCTAAACTCGTTGAAGGT
GAACGCGAGAAATTACTACGCTTAGAGCAAATCTTATCAGAGCGTGTCATCGGACAAGAGGAAGCAGTAAGCTTAGTATC
AGACGCGGTTCTTCGTGCTCGCGCTGGTATTAAAGATCCGAACCGCCCGATTGGTTCCTTCATTTTCTTAGGCCCTACGG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGTATTGATATG
TCTGAGTATATGGAGAAACACGCAGTGTCACGCTTAATTGGTGCACCTCCTGGATATGTAGGATATGAAGAAGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCATATTCCGTTATTTTATTAGATGAAATTGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTGGACTTTAAAAACACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTACTAGATGGATTAGAAGAAGATGGCTCGATTAAAGAGGAATCAAGAGA
CCTTGTAATGGGGCAATTAAGAGGACATTTCCGCCCTGAATTTTTAAACCGTGTTGATGAAATTATTTTATTTAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGGCGTTTAGCTGACCGTCACATTACA
GTAGAATTAACAGACGCAGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTATGGAGCTCGTCCATTAAAACG
ATACGTACAACGTCAAGTGGAAACGAAATTAGCGCGAGAATTAATTGCAGGAACAATTACTGACAATAGTCACGTAGTTG
TCGATGTAGAAAATAACGAATTAGTTGTTCATGTGAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.039	100	0.424
clpC	Lactococcus lactis subsp. cremoris KW2	47.199	82.448	0.389