Detailed information NTG0174481

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A2G56_RS06245
• Genome accession: NZ_CP014835
• Coordinates: 1390108..1392546 (-)
• Length: 812 a.a.
• NCBI ID: WP_062710487.1
• Uniprot ID: -
• Organism: Streptococcus halotolerans strain HTS9
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1385108..1397546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2G56_RS06220	-	1386138..1386641 (-)	504	WP_157761204.1	TlpA family protein disulfide reductase	-
A2G56_RS11170	-	1386638..1386895 (-)	258	WP_418080403.1	hypothetical protein	-
A2G56_RS06230	-	1387235..1388602 (-)	1368	WP_062710482.1	hypothetical protein	-
A2G56_RS06235	-	1388547..1389275 (-)	729	WP_062710484.1	ATP-binding cassette domain-containing protein	-
A2G56_RS06240	-	1389331..1389576 (-)	246	WP_237334393.1	hypothetical protein	-
A2G56_RS06245	clpC	1390108..1392546 (-)	2439	WP_062710487.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
A2G56_RS06250	-	1392546..1393007 (-)	462	WP_062710490.1	CtsR family transcriptional regulator	-
A2G56_RS06255	-	1393321..1393506 (-)	186	WP_062710493.1	hypothetical protein	-
A2G56_RS06260	tsf	1393872..1394912 (-)	1041	WP_062710495.1	translation elongation factor Ts	-
A2G56_RS06265	rpsB	1395099..1395866 (-)	768	WP_062710498.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 812 a.a.
• Molecular weight: 90135.25 Da
• Isoelectric Point: 5.2352

>NTDB_id=174481 A2G56_RS06245 WP_062710487.1 1390108..1392546(-) (clpC) [Streptococcus halotolerans strain HTS9]
MVKYSQKMQEVFGLSQIIATQFSCQLLESWHLLLGLISSDETIAGLTFREFDSETGENDYFAAAILASEKTFDESINQFD
LHEQSVATADILAFAEQISQITGDDEVGTEHVLMAMLLNPQMMPIRILELAGFKLKNDGEGSSIFSLRQSLEKHAGFTKD
QVKSIHELKKPKRPKANNFTDMMKPPSTAGELSDFTRDLTAMAQAGALETVVGRDKEISRMVQVLSRKTKNNPVLVGDAG
VGKTALAYGLAQRIAGGDIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIEDIETDGHIILFVDEMHTIMGSGSGM
DSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKIIIEEPAVEDAFEILKGLRPSYEAYHHVSISDDA
LMTAVKAAHRYMTSKNLPDSAIDLIDEASATVQTMVKKEVQAELSPIDEALLSGDLKTVSRLLKKEDTLATPKIVKVSED
HIMATLSRLTGIPVEKMTQADNQKYLNLEKELHKRVIGQDTAISAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTEL
AKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRQKPYSVLLFDEVEKAHPDIFNVLLQVL
DDGVSTDSRGRKVDFSNTLIIMTSNLGATALRDDKTVGFGAQDLSHDHEAMEKRILEELKKAYRPEFINRIDEKVVFHSL
TQDHMKEVVKIMVQPLIKQLAEKDIVLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLAELVLSGELAAGNILKI
GVKQGKLKFDMV

Nucleotide

• Length: 2439 bp

>NTDB_id=174481 A2G56_RS06245 WP_062710487.1 1390108..1392546(-) (clpC) [Streptococcus halotolerans strain HTS9]
ATGGTTAAGTATTCACAAAAAATGCAGGAAGTTTTTGGCCTGTCACAAATTATTGCAACACAGTTCTCTTGCCAATTGCT
AGAAAGTTGGCATCTTTTGCTTGGATTAATTTCCAGTGATGAAACCATTGCAGGATTAACTTTCCGAGAATTTGACAGTG
AGACTGGTGAAAATGATTATTTTGCAGCTGCTATTTTAGCGTCGGAGAAGACTTTTGATGAGAGCATTAATCAGTTTGAT
CTTCATGAGCAATCAGTAGCGACCGCTGACATCTTGGCTTTTGCGGAACAAATTAGTCAGATTACTGGAGATGACGAGGT
TGGTACTGAGCATGTCTTGATGGCGATGCTCCTAAATCCGCAAATGATGCCCATCCGTATCTTGGAATTAGCTGGATTTA
AACTCAAAAACGATGGTGAGGGGTCTTCGATTTTTAGTCTCCGTCAAAGTTTAGAGAAGCATGCGGGCTTTACCAAAGAT
CAAGTCAAATCCATTCACGAGTTGAAAAAACCCAAACGCCCTAAGGCTAATAATTTCACAGATATGATGAAACCACCATC
AACAGCTGGAGAATTATCGGATTTCACACGCGATTTAACAGCTATGGCGCAGGCTGGCGCTTTAGAAACGGTTGTGGGCC
GCGACAAAGAAATTTCTCGTATGGTACAGGTGCTCAGTCGTAAAACTAAGAATAATCCCGTCCTAGTCGGTGATGCTGGT
GTTGGTAAAACAGCTTTGGCTTATGGTTTAGCCCAACGCATTGCTGGTGGTGACATTCCTTATGAGCTGCGTGATATGCG
AGTTCTGGAATTAGATATGATGAGCGTGGTTGCAGGAACCCGATTCCGTGGTGATTTTGAGGAGCGTATGAATCAAATCA
TCGAAGATATCGAGACGGATGGGCATATTATCCTCTTTGTGGATGAAATGCACACGATTATGGGTTCTGGCAGTGGGATG
GACAGTACCTTGGATGCGGCTAATATTCTCAAACCAGCTCTTTCTCGTGGCACCCTCCATATGGTTGGCGCAACCACCCA
AGAAGAATACCAAAAGCATATTGAAAAAGATGCAGCGCTGTCGCGCCGTTTTGCTAAAATCATTATTGAAGAGCCTGCTG
TTGAAGATGCCTTTGAGATTCTCAAAGGACTTCGTCCGAGTTATGAAGCCTATCATCATGTATCGATTTCGGATGATGCC
CTGATGACAGCTGTTAAAGCTGCTCATCGTTATATGACCAGTAAAAACCTTCCGGACTCGGCTATCGATTTGATAGATGA
GGCTAGTGCGACTGTTCAAACCATGGTAAAAAAAGAAGTTCAAGCAGAGCTTTCGCCAATTGATGAAGCACTTTTAAGTG
GAGATCTCAAGACTGTTTCGCGTTTACTTAAAAAAGAAGACACCCTTGCTACTCCCAAAATTGTCAAGGTAAGCGAAGAC
CATATCATGGCTACTCTTAGTCGTCTGACAGGGATTCCTGTGGAAAAAATGACGCAGGCAGATAATCAAAAGTATCTTAA
TTTGGAAAAAGAATTACATAAACGTGTTATTGGTCAAGATACAGCAATTTCGGCTATCAGTCGTGCGATTCGTCGTAATC
AGTCTGGCATTCGAACTGGTAAACGTCCAATTGGGTCTTTCATGTTCTTGGGACCGACTGGGGTTGGTAAGACAGAGTTG
GCTAAGGCCTTAGCAGAAGTTCTTTTCGATGATGAATCAGCCCTTATTCGTTTTGATATGTCTGAATACATGGAGAAATT
TGCCGCTTCACGTCTGAACGGTGCCCCTCCAGGATATGTTGGTTACGATGAGGGGGGCGAACTGACAGAAAAAGTTCGTC
AGAAACCTTATTCGGTTCTCTTGTTCGATGAGGTTGAAAAGGCCCATCCTGATATTTTCAATGTGCTACTTCAAGTGCTT
GACGATGGTGTTTCAACAGATTCTCGTGGGCGCAAGGTTGATTTTTCAAATACCCTGATTATTATGACTTCAAACCTTGG
GGCGACGGCACTTCGTGATGATAAGACAGTCGGTTTTGGAGCGCAAGATCTATCACATGACCATGAGGCGATGGAAAAAC
GTATCTTGGAAGAACTTAAGAAGGCTTATCGTCCTGAGTTCATCAATCGTATTGATGAAAAAGTTGTCTTCCACAGCTTG
ACGCAAGACCACATGAAAGAAGTGGTTAAGATTATGGTTCAACCGTTGATTAAACAATTGGCTGAAAAAGATATTGTTCT
TAAATTCCAGCCGTCAGCTCTCAAACATTTGGCTGAGGATGGCTATGATATTGAAATGGGTGCACGTCCACTGCGCCGTA
CTATCCAGACACAAGTGGAAGATCACTTGGCAGAACTGGTTCTTTCAGGGGAACTAGCTGCTGGTAATATTCTCAAAATC
GGTGTCAAACAAGGGAAACTTAAATTTGATATGGTTTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (234-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (542-713)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-136)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (720-798)

• AAA lid domain (AAA_lid_9) (374-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	71.71	100	0.718
clpC	Streptococcus thermophilus LMG 18311	70.135	100	0.706
clpC	Streptococcus thermophilus LMD-9	70.135	100	0.706
clpC	Streptococcus pneumoniae Rx1	65.314	100	0.654
clpC	Streptococcus pneumoniae D39	65.314	100	0.654
clpC	Streptococcus pneumoniae TIGR4	65.068	100	0.651
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.865	100	0.504
clpC	Bacillus subtilis subsp. subtilis str. 168	44.258	100	0.456