Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   BSR20_RS00320 Genome accession   NZ_CP018189
Coordinates   54433..56370 (+) Length   645 a.a.
NCBI ID   WP_021143432.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 49433..61370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR20_RS00290 (BSR20_00290) argR 49638..50066 (+) 429 WP_170314548.1 arginine repressor -
  BSR20_RS00295 (BSR20_00295) - 50066..50425 (+) 360 WP_045772359.1 YlbF family regulator -
  BSR20_RS00300 (BSR20_00300) hexA 50445..52976 (+) 2532 WP_414355357.1 DNA mismatch repair protein MutS Machinery gene
  BSR20_RS00305 (BSR20_00305) - 53010..53465 (-) 456 WP_049527571.1 DUF3021 domain-containing protein -
  BSR20_RS00310 (BSR20_00310) - 53462..53899 (-) 438 WP_045772361.1 LytTR family DNA-binding domain-containing protein -
  BSR20_RS00315 (BSR20_00315) - 54078..54383 (+) 306 WP_002886319.1 hypothetical protein -
  BSR20_RS00320 (BSR20_00320) hexB 54433..56370 (+) 1938 WP_021143432.1 DNA mismatch repair endonuclease MutL Machinery gene
  BSR20_RS00325 (BSR20_00325) - 56501..56722 (+) 222 WP_002886321.1 hypothetical protein -
  BSR20_RS00330 (BSR20_00330) ruvA 56879..57469 (+) 591 WP_014633718.1 Holliday junction branch migration protein RuvA Machinery gene
  BSR20_RS00335 (BSR20_00335) - 57478..58032 (+) 555 WP_014633717.1 DNA-3-methyladenine glycosylase I -
  BSR20_RS00340 (BSR20_00340) cinA 58129..59397 (+) 1269 WP_045772364.1 competence/damage-inducible protein A Machinery gene
  BSR20_RS00345 (BSR20_00345) recA 59433..60572 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72273.34 Da        Isoelectric Point: 5.2797

>NTDB_id=173690 BSR20_RS00320 WP_021143432.1 54433..56370(+) (hexB) [Streptococcus salivarius strain ICDC3]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRSVDEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=173690 BSR20_RS00320 WP_021143432.1 54433..56370(+) (hexB) [Streptococcus salivarius strain ICDC3]
ATGCCAAAAATCATCGAATTGCCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGTCCAGCTAGTGT
TGTCAAAGAGTTAGTGGAAAATGCTATTGATGCAGGTAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTAAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGATATGGCTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCTTACT
TGGCCGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCA
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTACGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCAGAGTCACCAGTTTCATCGGTAGAAAATAAACCGCAACCT
TCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAACTCTGGATAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TATCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCAGA
CTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAACAACACTTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTCACGGAC
GTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGTCTACGT
GACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(446-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.665

100

0.709