Detailed information NTG0173548

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: BSR14_RS08615
• Genome accession: NZ_CP018186
• Coordinates: 1871718..1872458 (+)
• Length: 246 a.a.
• NCBI ID: WP_156209945.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC1
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1866718..1877458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR14_RS10490 (BSR14_08675)	-	1868192..1868443 (+)	252	Protein_1648	bacteriocin ABC transporter ATP-binding protein	-
BSR14_RS08590	-	1868496..1869625 (-)	1130	Protein_1649	IS3 family transposase	-
BSR14_RS08595 (BSR14_08690)	-	1869725..1870657 (-)	933	WP_156209941.1	thioredoxin family protein	-
BSR14_RS08600 (BSR14_08695)	-	1870823..1871002 (-)	180	WP_156209942.1	bacteriocin transporter	-
BSR14_RS08605 (BSR14_08700)	-	1871040..1871291 (-)	252	WP_156209943.1	bacteriocin immunity protein	-
BSR14_RS08610 (BSR14_08705)	-	1871257..1871481 (-)	225	WP_156209944.1	leucocin A/sakacin P family class II bacteriocin	-
BSR14_RS08615 (BSR14_08710)	comE/blpR	1871718..1872458 (+)	741	WP_156209945.1	LytR/AlgR family response regulator transcription factor	Regulator
BSR14_RS10615 (BSR14_08715)	-	1872543..1872944 (-)	402	WP_156209946.1	hypothetical protein	-
BSR14_RS10385	-	1873274..1873441 (-)	168	WP_197090282.1	hypothetical protein	-
BSR14_RS08630 (BSR14_08725)	-	1873900..1873989 (-)	90	WP_073688908.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
BSR14_RS10495	-	1874129..1874296 (-)	168	WP_049527516.1	hypothetical protein	-
BSR14_RS08635 (BSR14_08730)	-	1874312..1874491 (-)	180	WP_021152528.1	Blp family class II bacteriocin	-
BSR14_RS08640 (BSR14_08735)	-	1874652..1876397 (-)	1746	WP_156209948.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28291.91 Da
• Isoelectric Point: 9.2009

>NTDB_id=173548 BSR14_RS08615 WP_156209945.1 1871718..1872458(+) (comE/blpR) [Streptococcus salivarius strain ICDC1]
MKIYLLEDNPIQMGRLENALAQELKTFGKNLSCVHSFDKPDQLLSAITSNISDQVFFLDIEIKGEKLKGLDIAKIIRGKN
PYATIIFVATHSEYMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENGEIFDFQTQHTAIRIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPYNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
NRRKLD

Nucleotide

• Length: 741 bp

>NTDB_id=173548 BSR14_RS08615 WP_156209945.1 1871718..1872458(+) (comE/blpR) [Streptococcus salivarius strain ICDC1]
ATGAAGATTTACTTATTAGAAGATAATCCTATTCAGATGGGACGTTTAGAAAATGCTCTAGCTCAGGAACTTAAGACCTT
CGGAAAAAATCTATCGTGTGTTCACTCTTTTGACAAGCCAGATCAACTACTATCTGCTATCACCTCAAATATAAGCGATC
AGGTTTTCTTTCTGGATATTGAAATTAAAGGAGAGAAATTAAAAGGGCTTGACATTGCCAAAATCATTAGAGGAAAAAAT
CCCTATGCTACTATTATCTTTGTCGCTACTCACTCAGAGTATATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATCGACAAAAGTCTCTCTGAAATAGAATTTAGAAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GGATAGAAAATGGCGAGATTTTTGATTTTCAAACACAACATACAGCTATTCGCATCCCTTTGAATCAAGTTATTTATATT
GAAACTTCTCCACAAAAGCATTATGTGATACTTCATGGTACAAACAACCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCACCGTTCATATCTTATTAACCCATACAACATTATAAGAATCAACAAAT
TAAAGCGTGAAGTCGAAATGACTGATGGCAGTATCTGTCCTTTTTCACGTACCAAAGCTAAGATGCTGATGGATACTTTT
AATCGAAGAAAGCTTGACTAG

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-122)

• LytTr DNA-binding domain (LytTR) (150-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	42.553	95.528	0.407
comE/comE2	Streptococcus equinus JB1	37.975	96.341	0.366